Antimicrobial Activity of Artemisinin and Precursor Derived from In Vitro Plantlets of Artemisia annua L.
المؤلفون المشاركون
Ch'ng, Song Jin
Chan, Lai-Keng
Othman, Ahmad Sofiman
Lo, Kiah Yann
Appalasamy, Suganthi
Nornadia, Ku
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-01-19
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Artemisia annua L., a medicinal herb, produces secondary metabolites with antimicrobial property.
In Malaysia due to the tropical hot climate, A.
annua could not be planted for production of artemisinin, the main bioactive compound.
In this study, the leaves of three in vitro A.
annua L.
clones were, extracted and two bioactive compounds, artemisinin and a precursor, were isolated by thin layer chromatography.
These compounds were found to be effective in inhibiting the growth of Gram-positive and Gram-negative bacteria but not Candida albicans.
Their antimicrobial activity was similar to that of antibactericidal antibiotic streptomycin.
They were found to inhibit the growth of the tested microbes at the minimum inhibition concentration of 0.09 mg/mL, and toxicity test using brine shrimp showed that even the low concentration of 0.09 mg/mL was very lethal towards the brine shrimps with 100% mortality rate.
This study hence indicated that in vitro cultured plantlets of A.
annua can be used as the alternative method for production of artemisinin and its precursor with antimicrobial activities.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Appalasamy, Suganthi& Lo, Kiah Yann& Ch'ng, Song Jin& Nornadia, Ku& Othman, Ahmad Sofiman& Chan, Lai-Keng. 2014. Antimicrobial Activity of Artemisinin and Precursor Derived from In Vitro Plantlets of Artemisia annua L.. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-455253
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Appalasamy, Suganthi…[et al.]. Antimicrobial Activity of Artemisinin and Precursor Derived from In Vitro Plantlets of Artemisia annua L.. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-455253
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Appalasamy, Suganthi& Lo, Kiah Yann& Ch'ng, Song Jin& Nornadia, Ku& Othman, Ahmad Sofiman& Chan, Lai-Keng. Antimicrobial Activity of Artemisinin and Precursor Derived from In Vitro Plantlets of Artemisia annua L.. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-455253
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-455253
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر