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Family History of Cancer and Tobacco Exposure in Index Cases of Pancreatic Ductal Adenocarcinoma
المؤلفون المشاركون
Reeves, H. L.
Charnley, Richard M.
Daly, Anne K.
Lochan, Rajiv
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-04-06
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Aim.
To examine interaction between history of cancer in first-degree relatives and tobacco smoking in index patients of pancreatic adenocarcinoma.
Methods.
We carried out a case-control involving 113 patients with pancreatic adenocarcinoma and 110 controls over a 12-month period at the Freeman Hospital, Newcastle upon Tyne, UK.
They were all administered a detailed tobacco exposure questionnaire and a family history questionnaire.
We calculated cumulative tobacco exposure and risk for pancreas cancer.
Results.
Both smokers (OR 3.01 (95% CI: 1.73 to 5.24)) and those with a family history of malignancy (OR 1.98 (95% CI: 1.15–3.38)) were more likely to develop pancreatic cancer.
Having more than one first-degree relative with cancer did not significantly further increase the risk of pancreatic cancer.
Amongst pancreatic cancer cases, cumulative tobacco exposure was significantly decreased (P=.032) in the group of smokers (current and ex-smokers) who had a family history of malignancy [mean (SD): 30.00 (24.77) pack-years versus 44.69 (28.47) pack-years with no such history].
Conclusions.
Individuals with a family history of malignancy are at an increased risk of pancreatic cancer.
Furthermore, individuals with a family history of malignancy and who smoke appear to require a lesser degree of tobacco exposure for the development of pancreatic cancer.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lochan, Rajiv& Daly, Anne K.& Reeves, H. L.& Charnley, Richard M.. 2011. Family History of Cancer and Tobacco Exposure in Index Cases of Pancreatic Ductal Adenocarcinoma. Journal of Oncology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-455259
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lochan, Rajiv…[et al.]. Family History of Cancer and Tobacco Exposure in Index Cases of Pancreatic Ductal Adenocarcinoma. Journal of Oncology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-455259
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lochan, Rajiv& Daly, Anne K.& Reeves, H. L.& Charnley, Richard M.. Family History of Cancer and Tobacco Exposure in Index Cases of Pancreatic Ductal Adenocarcinoma. Journal of Oncology. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-455259
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-455259
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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