The Comparative Study of the Effectiveness of Cimetidine, Ranitidine, Famotidine, and Omeprazole in Treatment of Children with Dyspepsia
المؤلفون المشاركون
Haghighat, Mahmood
Imanieh, Mohammad Hadi
Oboodi, Roya
Dehghani, Seyed Mohsen
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-04-05
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
العلوم الطبية والصيدلة والعلوم الصحية
علم الصيدلة
الملخص EN
Background.
Functional dyspepsia is a common chronic disorder with non specific upper abdominal pain or discomfort.
Different approaches with anti-secretory, spasmolytic, prokinetic and anti-inflammatory effects and most preferably reduction of visceral hypersensitivity seem logical.
In this study, we compared the effectiveness of the four most drugs used for treatment of dyspepsia in children.
Methods.
169 patients between 2 to 16 years old that 47.3% was male and 52.7% was female were enrolled in this clinical trial study by the diagnosis of functional dyspepsia.
Then for each patient one of the drugs; Omeprazole, Famotidine, Ranitidine or Cimetidine was administered, for a period of 4 weeks.
Patients were followed after 2 and 6 weeks from the beginning of the treatment.
Results.
The distribution of drugs between these patients were including; 21.9% with Cimetidine, 21.3% with Famotidine, 30.8% with Omeperazole and 26% with Ranitidine that the proportion of patients with all symptoms relief were: 21.6% for Cimetidine, 44.4% for Famotidine, 53.8% for Omeprazole and 43.2% for Cimetidine (P=.024).
In followups within 2 and 6 weeks after beginning medical therapy, no side effects due to drugs were seen.
Conclusion.
If a cure is defined as all symptoms relief after a period of 4 weeks treatment, our findings showed that Omeperazole are superior to Ranitidine, Famotidine, and Cimetidine for management of functional dyspepsia.Erratum to “The Comparative Study of the Effectiveness of Cimetidine, Ranitidine, Famotidine, and Omeprazole in Treatment of Children with Dyspepsia”dx.doi.org/10.1155/2013/206546
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dehghani, Seyed Mohsen& Imanieh, Mohammad Hadi& Oboodi, Roya& Haghighat, Mahmood. 2011. The Comparative Study of the Effectiveness of Cimetidine, Ranitidine, Famotidine, and Omeprazole in Treatment of Children with Dyspepsia. ISRN Pediatrics،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-455581
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dehghani, Seyed Mohsen…[et al.]. The Comparative Study of the Effectiveness of Cimetidine, Ranitidine, Famotidine, and Omeprazole in Treatment of Children with Dyspepsia. ISRN Pediatrics No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-455581
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dehghani, Seyed Mohsen& Imanieh, Mohammad Hadi& Oboodi, Roya& Haghighat, Mahmood. The Comparative Study of the Effectiveness of Cimetidine, Ranitidine, Famotidine, and Omeprazole in Treatment of Children with Dyspepsia. ISRN Pediatrics. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-455581
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-455581
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر