Exercise Training Could Improve Age-Related Changes in Cerebral Blood Flow and Capillary Vascularity through the Upregulation of VEGF and eNOS
المؤلفون المشاركون
Patumraj, Suthiluk
Viboolvorakul, Sheepsumon
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-13
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
This study aimed to investigate the effect of exercise training on age-induced microvascular alterations in the brain.
Additionally, the association with the protein levels of vascular endothelial growth factor (VEGF) and endothelial nitric oxide synthase (eNOS) was also assessed.
Male Wistar rats were divided into four groups: sedentary-young (SE-Young, n=5), sedentary aged (SE-Aged, n=8), immersed-aged (IM-Aged, n=5), and exercise trained-aged (ET-Aged, 60 minutes/day and 5 days/week for 8 weeks, n=8) rats.
The MAPs of all aged groups, SE-Aged, IM-Aged, and ET-Aged, were significantly higher than that of the SE-Young group.
The regional cerebral blood flow (rCBF) in the SE-Aged and IM-Aged was significantly decreased as compared to SE-Young groups.
However, rCBF of ET-Aged group was significantly higher than that in the IM-Aged group (P<0.05).
Moreover, the percentage of capillary vascularity (%CV) and the levels of VEGF and eNOS in the ET-Aged group were significantly increased compared to the IM-Aged group (P<0.05).
These results imply that exercise training could improve age-induced microvascular changes and hypoperfusion closely associated with the upregulation of VEGF and eNOS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Viboolvorakul, Sheepsumon& Patumraj, Suthiluk. 2014. Exercise Training Could Improve Age-Related Changes in Cerebral Blood Flow and Capillary Vascularity through the Upregulation of VEGF and eNOS. BioMed Research International،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-455729
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Viboolvorakul, Sheepsumon& Patumraj, Suthiluk. Exercise Training Could Improve Age-Related Changes in Cerebral Blood Flow and Capillary Vascularity through the Upregulation of VEGF and eNOS. BioMed Research International No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-455729
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Viboolvorakul, Sheepsumon& Patumraj, Suthiluk. Exercise Training Could Improve Age-Related Changes in Cerebral Blood Flow and Capillary Vascularity through the Upregulation of VEGF and eNOS. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-455729
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-455729
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر