Cell Stress Proteins in Atherothrombosis
المؤلفون المشاركون
Blanco-Colio, Luis Miguel
Martinez-Pinna, Roxana
Jose Luis, Martin-Ventura
Fernandez-Garcia, Carlos Ernesto
Madrigal-Matute, Julio
Egido, Jesus
Burillo, Elena
Ramos-Mozo, Priscila
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-06-25
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الأحياء
الملخص EN
Cell stress proteins (CSPs) are a large and heterogenous family of proteins, sharing two main characteristics: their levels and/or location are modified under stress and most of them can exert a chaperon function inside the cells.
Nonetheless, they are also involved in the modulation of several mechanisms, both at the intracellular and the extracellular compartments.
There are more than 100 proteins belonging to the CSPs family, among them the thioredoxin (TRX) system, which is the focus of the present paper.
TRX system is composed of several proteins such as TRX and peroxiredoxin (PRDX), two thiol-containing enzymes that are key players in redox homeostasis due to their ability to scavenge potential harmful reactive oxygen species.
In addition to their main role as antioxidants, recent data highlights their function in several processes such as cell signalling, immune inflammatory responses, or apoptosis, all of them key mechanisms involved in atherothrombosis.
Moreover, since TRX and PRDX are present in the pathological vascular wall and can be secreted under prooxidative conditions to the circulation, several studies have addressed their role as diagnostic, prognostic, and therapeutic biomarkers of cardiovascular diseases (CVDs).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Madrigal-Matute, Julio& Martinez-Pinna, Roxana& Fernandez-Garcia, Carlos Ernesto& Ramos-Mozo, Priscila& Burillo, Elena& Egido, Jesus…[et al.]. 2012. Cell Stress Proteins in Atherothrombosis. Oxidative Medicine and Cellular Longevity،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-455891
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Madrigal-Matute, Julio…[et al.]. Cell Stress Proteins in Atherothrombosis. Oxidative Medicine and Cellular Longevity No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-455891
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Madrigal-Matute, Julio& Martinez-Pinna, Roxana& Fernandez-Garcia, Carlos Ernesto& Ramos-Mozo, Priscila& Burillo, Elena& Egido, Jesus…[et al.]. Cell Stress Proteins in Atherothrombosis. Oxidative Medicine and Cellular Longevity. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-455891
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-455891
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر