The Preoperative Maximum Standardized Uptake Value Measured by 18F-FDG PETCT as an Independent Prognostic Factor of Overall Survival in Endometrial Cancer Patients
المؤلفون المشاركون
Walentowicz, Pawel
Marszalek, Andrzej
Pietrzak, Tomasz
Małkowski, Bogdan
Walentowicz-Sadlecka, Małgorzata
Grabiec, Marek
Sadlecki, Pawel
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-01-20
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Purpose.
The aim of this study was to determine if the preoperative maximum standardized uptake value (SUVmax) measured by 18F-FDG PET/CT in the primary tumor has prognostic value in the group of patients with endometrial cancer.
Patients, Materials, and Methods.
A total of one hundred one consecutive endometrial cancer patients, age range 40–82 years (mean 62 years) and FIGO I–IV stage, who underwent 18-FDG-PET/CT within two weeks prior radical surgery, were enrolled to the study.
The maximum SUV was measured and compared with the clinicopathologic features of surgical specimens.
The relationship between SUVmax and overall survival was analyzed.
Results.
The mean preoperative SUVmax was 14.34; range (3.90–33.80) and was significantly lower for FIGO I than for higher stages (P=0.0012), as well as for grade 1 than for grade 2 and 3 (P=0.018), deep myometrial invasion (P=0.0016) and for high risk group (P=0.0004).
The analysis of survival ROC curve revealed SUVmax cut-off value of 17.7 to predict high risk of recurrence.
Endometrial cancer patients with SUVmax higher than 17.7 characterized by lower overall survival.
Conclusion.
The preoperative SUVmax measured by 18F-FDG PET/CT is considered as an important indicator reflecting tumor aggressiveness which may predict poor prognosis.
High value of SUVmax would be useful for making noninvasive diagnoses and deciding the appropriate therapeutic strategy for patients with endometrial cancer.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Walentowicz-Sadlecka, Małgorzata& Małkowski, Bogdan& Walentowicz, Pawel& Sadlecki, Pawel& Marszalek, Andrzej& Pietrzak, Tomasz…[et al.]. 2014. The Preoperative Maximum Standardized Uptake Value Measured by 18F-FDG PETCT as an Independent Prognostic Factor of Overall Survival in Endometrial Cancer Patients. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-456009
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Walentowicz-Sadlecka, Małgorzata…[et al.]. The Preoperative Maximum Standardized Uptake Value Measured by 18F-FDG PETCT as an Independent Prognostic Factor of Overall Survival in Endometrial Cancer Patients. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-456009
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Walentowicz-Sadlecka, Małgorzata& Małkowski, Bogdan& Walentowicz, Pawel& Sadlecki, Pawel& Marszalek, Andrzej& Pietrzak, Tomasz…[et al.]. The Preoperative Maximum Standardized Uptake Value Measured by 18F-FDG PETCT as an Independent Prognostic Factor of Overall Survival in Endometrial Cancer Patients. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-456009
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-456009
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر