First Danish Single-Institution Experience with Radical Prostatectomy : Biochemical Outcome in 1200 Consecutive Patients
المؤلفون المشاركون
Berg, Kasper D.
Røder, M. Andreas
Gruschy, Lisa
Iversen, Peter
Brasso, Klaus
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-12-22
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Radical retropubic prostatectomy (RRP) as intended curative therapy for patients with clinically localized prostate cancer (PC) was initiated in 1995 in Denmark.
This paper reports single-institution results from the first 1200 consecutive patients operated during a 15-year period.
Median age at surgery was 63 years.
Median PSA was 9 ng/mL.
Palpable tumors (≤cT2) were present in 48% of patients.
Gleason score at biopsy was ≤7 for 85% of patients.
In sixty-five percent of patients, histopathology revealed localized PCa after RRP.
Positive surgical margins were found in 39.2% of the cases.
Biochemical recurrence (BR) occurred for 214 (18%) of patients.
The estimated biochemical recurrence free survival (BRFS) was 71.7% and 63.2% after 5 and 10 years, respectively.
When patients were stratified according to the D'Amico criteria, BRFS after 10 years was 75.3%, 59.7%, and 39.3% for low-, medium- and high-risk patients, respectively.
In univariate analysis, clinical stage, PSA at diagnosis and type of surgery were significant predictors of BR.
In multivariate analysis, Gleason score > 7, PSA > 10, and higher clinical stage were significant predictors of BR.
Early Danish results in a population not subjected to screening demonstrate BRFS rates comparable with earlier reports from the prescreening era.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Røder, M. Andreas& Berg, Kasper D.& Gruschy, Lisa& Brasso, Klaus& Iversen, Peter. 2010. First Danish Single-Institution Experience with Radical Prostatectomy : Biochemical Outcome in 1200 Consecutive Patients. Prostate Cancer،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-456151
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Røder, M. Andreas…[et al.]. First Danish Single-Institution Experience with Radical Prostatectomy : Biochemical Outcome in 1200 Consecutive Patients. Prostate Cancer No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-456151
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Røder, M. Andreas& Berg, Kasper D.& Gruschy, Lisa& Brasso, Klaus& Iversen, Peter. First Danish Single-Institution Experience with Radical Prostatectomy : Biochemical Outcome in 1200 Consecutive Patients. Prostate Cancer. 2010. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-456151
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-456151
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر