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The Impact of Pulmonary Arterial Pressure on Exercise Capacity in Mild-to-Moderate Cystic Fibrosis : A Case Control Study
المؤلفون المشاركون
Stanopoulos, Ioannis
Boutou, Afroditi K.
Kioumis, Ioannis
Pitsiou, Georgia G.
Tsaoussis, Vassilis
Antoniou, Marina
Fotoulaki, Maria
Manika, Katerina
Chavouzis, Nikolaos
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-07-29
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Pulmonary hypertension (PH) is an often complication of severe cystic fibrosis (CF); however, data on the presence and impact of pulmonary vasculopathy in adult CF patients with milder disease, is very limited.
Aim.
To investigate, for the first time, the impact of systolic pulmonary arterial pressure (PASP) on maximal exercise capacity in adults with mild-to-moderate cystic fibrosis, without PH at rest.
Methods.
This is a Case Control study.
Seventeen adults with mild-to-moderate CF, without PH at rest (cases) and 10 healthy, nonsmoking, age, and height matched controls were studied.
All subjects underwent maximal cardiopulmonary exercise testing and echocardiography before and within 1 minute after stopping exercise.
Results.
Exercise ventilation parameters were similar in the two groups; however, cases, compared to controls, had higher postexercise PASP and decreased exercise capacity, established with lower peak work rate, peak O2 uptake, anaerobic threshold, and peak O2 pulse.
Furthermore, the change in PASP values before and after exercise was strongly correlated to the parameters of exercise capacity among cases but not among controls.
Conclusions.
CF adults with mild-to-moderate disease should be screened for the presence of pulmonary vasculopathy, since the elevation of PASP during exercise might contribute to impaired exercise capacity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Manika, Katerina& Pitsiou, Georgia G.& Boutou, Afroditi K.& Tsaoussis, Vassilis& Chavouzis, Nikolaos& Antoniou, Marina…[et al.]. 2012. The Impact of Pulmonary Arterial Pressure on Exercise Capacity in Mild-to-Moderate Cystic Fibrosis : A Case Control Study. Pulmonary Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-457572
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Manika, Katerina…[et al.]. The Impact of Pulmonary Arterial Pressure on Exercise Capacity in Mild-to-Moderate Cystic Fibrosis : A Case Control Study. Pulmonary Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-457572
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Manika, Katerina& Pitsiou, Georgia G.& Boutou, Afroditi K.& Tsaoussis, Vassilis& Chavouzis, Nikolaos& Antoniou, Marina…[et al.]. The Impact of Pulmonary Arterial Pressure on Exercise Capacity in Mild-to-Moderate Cystic Fibrosis : A Case Control Study. Pulmonary Medicine. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-457572
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-457572
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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