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Interleukin-6 and C-Reactive Protein Are Overexpressed in the Liver of Perinatal Deaths Diagnosed with Fetal Inflammatory Response Syndrome
المؤلفون المشاركون
Castellano, Lúcio Roberto
Corrêa, Rosana Rosa Miranda
Vinícius da Silva, Marcos
Rocha, Laura Penna
Guimarães, Camila S. O.
Olegário, Janaínna Grazielle Pacheco
Ramalho, Fernando S.
Reis, Marlene Antônia dos
Pereira, Lívia Helena M.
Machado, Juliana Reis
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-10
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Anatomopathologic studies have failed to define the fetal inflammatory response syndrome (FIRS) as a cause of fetal death.
Here, liver fragments of perinatal autopsies were collected at a university hospital from 1990 to 2009 and classified according to the cause of death, perinatal stress, and gestational age (GA) of the fetus.
IL-6, TNF-α, and C-reactive protein (CRP) expression were immunostained, respectively, with primary antibody.
Cases with congenital malformation, ascending infection, and perinatal anoxia showed increased IL-6, CRP, and TNF-α, respectively.
Prematures presented higher expression of IL-6 whereas term births showed higher expression of CRP.
Cases classified as acute stress presented higher expression of IL-6 and TNF-α and cases with chronic stress presented higher expression of CRP.
GA correlated negatively with IL-6 and positively with CRP and TNF-α.
Body weight correlated negatively with IL-6 and positively with CRP and TNF-α.
Despite the diagnosis of FIRS being clinical and based on serum parameters, the findings in the current study allow the inference of FIRS diagnosis in the autopsied infants, based on an in situ liver analysis of these markers.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pereira, Lívia Helena M.& Machado, Juliana Reis& Olegário, Janaínna Grazielle Pacheco& Rocha, Laura Penna& Vinícius da Silva, Marcos& Guimarães, Camila S. O.…[et al.]. 2014. Interleukin-6 and C-Reactive Protein Are Overexpressed in the Liver of Perinatal Deaths Diagnosed with Fetal Inflammatory Response Syndrome. Disease Markers،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-457602
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pereira, Lívia Helena M.…[et al.]. Interleukin-6 and C-Reactive Protein Are Overexpressed in the Liver of Perinatal Deaths Diagnosed with Fetal Inflammatory Response Syndrome. Disease Markers No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-457602
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pereira, Lívia Helena M.& Machado, Juliana Reis& Olegário, Janaínna Grazielle Pacheco& Rocha, Laura Penna& Vinícius da Silva, Marcos& Guimarães, Camila S. O.…[et al.]. Interleukin-6 and C-Reactive Protein Are Overexpressed in the Liver of Perinatal Deaths Diagnosed with Fetal Inflammatory Response Syndrome. Disease Markers. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-457602
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-457602
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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