Aqueous Extract of Black Maca (Lepidium meyenii) on Memory Impairment Induced by Ovariectomy in Mice
المؤلفون المشاركون
Chen, Shi Lin
Qiong, Wang
Dang, Haixia
Gonzales, Gustavo F.
Liu, Xin min
Rubio, Julio
Jiang, Zhen
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-02-14
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
The present study aims to test two different doses of aqueous extract of black maca on learning and memory in ovariectomized (OVX) mice and their relation with malonalehyde (MDA), acetylcholinesterase (Ache) and monoamine oxidase (MAO) brain levels.
Female mice were divided into five groups: (i) naive (control), (ii) sham, (iii) OVX mice and OVX mice treated with (iv) 0.50 g kg−1 and (v) 2.00 g kg−1 black maca.
Mice were orally treated with distilled water or black maca during 35 days starting 7 days after surgery.
Memory and learning were assessed using the water Morris maze (from day 23–27) and the step-down avoidance test (days 34 and 35).
At the end of each treatment, mice were sacrificed by decapitation and brains were dissected out for MDA, Ache and MAO determinations.
Black maca (0.5 and 2.0 g/kg) increased step-down latency when compared to OVX control mice.
Black maca decreased MDA and Ache levels in OVX mice; whereas, no differences were observed in MAO levels.
Finally, black maca improved experimental memory impairment induced by ovariectomy, due in part, by its antioxidant and Ache inhibitory activities.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rubio, Julio& Qiong, Wang& Liu, Xin min& Jiang, Zhen& Dang, Haixia& Chen, Shi Lin…[et al.]. 2011. Aqueous Extract of Black Maca (Lepidium meyenii) on Memory Impairment Induced by Ovariectomy in Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-457709
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rubio, Julio…[et al.]. Aqueous Extract of Black Maca (Lepidium meyenii) on Memory Impairment Induced by Ovariectomy in Mice. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-457709
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rubio, Julio& Qiong, Wang& Liu, Xin min& Jiang, Zhen& Dang, Haixia& Chen, Shi Lin…[et al.]. Aqueous Extract of Black Maca (Lepidium meyenii) on Memory Impairment Induced by Ovariectomy in Mice. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-457709
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-457709
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر