Noninvasive Evaluation of Nerve Conduction in Small Diameter Fibers in the Rat

المؤلفون المشاركون

Arezzo, Joseph C.
Zotova, Elena G.

المصدر

Physiology Journal

العدد

المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-11، 11ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2013-02-26

دولة النشر

مصر

عدد الصفحات

11

التخصصات الرئيسية

الأحياء
الطب البشري
علوم

الملخص EN

A novel noninvasive technique was applied to measure velocity within slow conducting axons in the distal extreme of the sciatic nerve (i.e., digital nerve) in a rat model.

The technique is based on the extraction of rectified multiple unit activity (MUA) from in vivo whole nerve compound responses.

This method reliably identifies compound action potentials in thinly myelinated fibers conducting at a range of 9–18 m/s (Aδ axons), as well as in a subgroup of unmyelinated C fibers conducting at approximately 1-2 m/s.

The sensitivity of the method to C-fiber conduction was confirmed by the progressive decrement of the responses in the 1-2 m/s range over a 20-day period following the topical application of capsaicin (ANOVA P<0.03).

Increasing the frequency of applied repetitive stimulation over a range of 0.75 Hz to 6.0 Hz produced slowing of conduction and a significant decrease in the magnitude of the compound C-fiber response (ANOVA P<0.01).

This technique offers a unique opportunity for the noninvasive, repeatable, and quantitative assessment of velocity in the subsets of Aδ and C fibers in parallel with the evaluation of fast nerve conduction.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Zotova, Elena G.& Arezzo, Joseph C.. 2013. Noninvasive Evaluation of Nerve Conduction in Small Diameter Fibers in the Rat. Physiology Journal،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-457793

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Zotova, Elena G.& Arezzo, Joseph C.. Noninvasive Evaluation of Nerve Conduction in Small Diameter Fibers in the Rat. Physiology Journal No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-457793

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Zotova, Elena G.& Arezzo, Joseph C.. Noninvasive Evaluation of Nerve Conduction in Small Diameter Fibers in the Rat. Physiology Journal. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-457793

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-457793