Reduced Treatment-Emergent Sexual Dysfunction as a Potential Target in the Development of New Antidepressants

المؤلفون المشاركون

Baldwin, David S.
Masdrakis, Vasilios G.
Palazzo, M. Carlotta

المصدر

Depression Research and Treatment

العدد

المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2013-02-04

دولة النشر

مصر

عدد الصفحات

8

التخصصات الرئيسية

الأمراض

الملخص EN

Pleasurable sexual activity is an essential component of many human relationships, providing a sense of physical, psychological, and social well-being.

Epidemiological and clinical studies show that depressive symptoms and depressive illness are associated with impairments in sexual function and satisfaction, both in untreated and treated patients.

The findings of randomized placebo-controlled trials demonstrate that most of the currently available antidepressant drugs are associated with the development or worsening of sexual dysfunction, in a substantial proportion of patients.

Sexual difficulties during antidepressant treatment often resolve as depression lifts but can endure over long periods and may reduce self-esteem and affect mood and relationships adversely.

Sexual dysfunction during antidepressant treatment is typically associated with many possible causes, but the risk and type of dysfunction vary with differing compounds and should be considered when making decisions about the relative merits and drawbacks of differing antidepressants.

A range of interventions can be considered when managing patients with sexual dysfunction associated with antidepressants, including the prescription of phosphodiesterase-5 inhibitors, but none of these approaches can be considered “ideal.” As treatment-emergent sexual dysfunction is less frequent with certain drugs, presumably related to differences in their pharmacological properties, and because current management approaches are less than ideal, a reduced burden of treatment-emergent sexual dysfunction represents a tolerability target in the development of novel antidepressants.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Baldwin, David S.& Palazzo, M. Carlotta& Masdrakis, Vasilios G.. 2013. Reduced Treatment-Emergent Sexual Dysfunction as a Potential Target in the Development of New Antidepressants. Depression Research and Treatment،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-457901

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Baldwin, David S.…[et al.]. Reduced Treatment-Emergent Sexual Dysfunction as a Potential Target in the Development of New Antidepressants. Depression Research and Treatment No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-457901

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Baldwin, David S.& Palazzo, M. Carlotta& Masdrakis, Vasilios G.. Reduced Treatment-Emergent Sexual Dysfunction as a Potential Target in the Development of New Antidepressants. Depression Research and Treatment. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-457901

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-457901