![](/images/graphics-bg.png)
Characterization of Stanniocalcin-1 Receptors in the Rainbow Trout
المؤلفون المشاركون
Fenton, Amanda L.
Richards, Timothy D. J.
Syed, Rahma
Wagner, Graham F.
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-02-06
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Mammalian stanniocalcin-1 (STC-1) is one of several ligands targeted to mitochondria.
High affinity STC-1 receptors are present on the mitochondrial membranes of nephron cells, myocytes, and hepatocytes, to enable ligand sequestration within the matrix.
However, STC-1 receptors have not been characterized in fish.
Nor is it known if mitochondrial targeting occurs in fish.
The aim of the study was to address these questions.
Saturation binding assays were carried out to obtain estimates of KD and Bmax.
They revealed the presence of saturable, high-affinity receptors on both membranes and mitochondria of liver, muscle, and gill filament.
In situ ligand binding (ISLB) was used to localize receptors at the histological level and revealed some unexpected findings.
In cranium, for instance, receptors were found mainly in the cartilage matrix, as opposed to the chondrocytes.
In brain, the majority of receptors were located on neuropil areas as opposed to neuronal cell bodies.
In skeletal muscle, receptors were confined to periodic striations, tentatively identified as the Z lines.
Receptors were even found on STC-1 producing corpuscles of Stannius cells, raising the possibility of there being an autocrine feedback loop or, perhaps, a soluble binding protein that is released with the ligand to regulate its bioavailability.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Richards, Timothy D. J.& Fenton, Amanda L.& Syed, Rahma& Wagner, Graham F.. 2012. Characterization of Stanniocalcin-1 Receptors in the Rainbow Trout. ISRN Endocrinology،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-458008
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Richards, Timothy D. J.…[et al.]. Characterization of Stanniocalcin-1 Receptors in the Rainbow Trout. ISRN Endocrinology No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-458008
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Richards, Timothy D. J.& Fenton, Amanda L.& Syed, Rahma& Wagner, Graham F.. Characterization of Stanniocalcin-1 Receptors in the Rainbow Trout. ISRN Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-458008
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-458008
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)