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The Establishment of Metabolic Syndrome Model by Induction of Fructose Drinking Water in Male Wistar Rats
المؤلفون المشاركون
Sapri, Shaiful Ridzwan
Zar Chi, Thent
Mohd Yusof, Mohd Rafizul
Sahruddin, Natasya Nadia
Mamikutty, Norshalizah
Haji Suhaimi, Farihah
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-18
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Metabolic syndrome can be caused by modification of diet by means of consumption of high carbohydrate and high fat diet such as fructose.
Aims.
To develop a metabolic syndrome rat model by induction of fructose drinking water (FDW) in male Wistar rats.
Methods.
Eighteen male Wistar rats were fed with FDW 20% and FDW 25% for a duration of eight weeks.
The physiological changes with regard to food and fluid intake, as well as calorie intake, were measured.
The metabolic changes such as obesity, dyslipidaemia, hypertension, and hyperglycaemia were determined.
Data was presented in mean ± SEM subjected to one-way ANOVA.
Results.
Male Wistar rats fed with FDW 20% for eight weeks developed significant higher obesity parameters compared to those fed with FDW 25%.
There was hypertrophy of adipocytes in F20 and F25.
There were also systolic hypertension, hypertriglyceridemia, and hyperglycemia in both groups.
Conclusion.
We conclude that the metabolic syndrome rat model is best established with the induction of FDW 20% for eight weeks.
This was evident in the form of higher obesity parameter which caused the development of the metabolic syndrome.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mamikutty, Norshalizah& Zar Chi, Thent& Sapri, Shaiful Ridzwan& Sahruddin, Natasya Nadia& Mohd Yusof, Mohd Rafizul& Haji Suhaimi, Farihah. 2014. The Establishment of Metabolic Syndrome Model by Induction of Fructose Drinking Water in Male Wistar Rats. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-458589
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mamikutty, Norshalizah…[et al.]. The Establishment of Metabolic Syndrome Model by Induction of Fructose Drinking Water in Male Wistar Rats. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-458589
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mamikutty, Norshalizah& Zar Chi, Thent& Sapri, Shaiful Ridzwan& Sahruddin, Natasya Nadia& Mohd Yusof, Mohd Rafizul& Haji Suhaimi, Farihah. The Establishment of Metabolic Syndrome Model by Induction of Fructose Drinking Water in Male Wistar Rats. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-458589
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-458589
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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