Patients with Mild Cognitive Impairment Display Reduced Auditory Event-Related Delta Oscillatory Responses
المؤلفون المشاركون
Yener, Görsev Gülmen
Turp, Bilge
Karşıdağ, Sibel
Emek-Savaş, Derya Durusu
Kurt, Pınar
Batum, Kübra
Güntekin, Bahar
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-27
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
Event-related oscillations (ERO) may provide a useful tool for the identification of cognitive deficits in mild cognitive impairment (MCI) and Alzheimer's disease (AD).
In the present study, we investigate peak-to-peak amplitude of auditory event-related delta oscillations of MCI subjects.
Method.
The study included twenty-two consecutive patients with MCI recruited in neurology clinic and 21 age- and education-matched normal elderly controls.
A classical auditory oddball paradigm was used in the experiments.
EEG was recorded from F3, Fz, F4, C3, Cz, C4, P3, Pz, P4, O1, Oz, and O2 locations.
The maximum peak-to-peak amplitudes for each subject’s averaged delta response (0.5–2.2 Hz) were measured.
Results.
The amplitudes between groups differed significantly at the frontal and mid-centroparietal locations.
ANOVA on delta responses revealed a significant effect for groups (F(1.41) = 4.84, P=0.033), indicating a larger delta response for healthy controls than MCI subjects.
Post hoc comparisons revealed that peak-to-peak delta response was significantly larger for healthy controls than for MCI over electrode sites F3, Fz, F4, Cz, C4, and Pz.
Discussion.
Event-related delta frequency band seems to be the most affected oscillatory response in cognitive impairment due to AD.
Therefore, it deserves to be investigated as a candidate electrophysiological biomarker in further studies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kurt, Pınar& Emek-Savaş, Derya Durusu& Batum, Kübra& Turp, Bilge& Güntekin, Bahar& Karşıdağ, Sibel…[et al.]. 2014. Patients with Mild Cognitive Impairment Display Reduced Auditory Event-Related Delta Oscillatory Responses. Behavioural Neurology،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-458972
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kurt, Pınar…[et al.]. Patients with Mild Cognitive Impairment Display Reduced Auditory Event-Related Delta Oscillatory Responses. Behavioural Neurology No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-458972
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kurt, Pınar& Emek-Savaş, Derya Durusu& Batum, Kübra& Turp, Bilge& Güntekin, Bahar& Karşıdağ, Sibel…[et al.]. Patients with Mild Cognitive Impairment Display Reduced Auditory Event-Related Delta Oscillatory Responses. Behavioural Neurology. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-458972
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-458972
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر