Amyloid-Beta Peptide, Oxidative Stress and Inflammation in Alzheimer's Disease : Potential Neuroprotective Effects of Omega-3 Polyunsaturated Fatty Acids
المؤلف
المصدر
International Journal of Alzheimer's Disease
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-06-14
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Alzheimer's disease is the most common form of dementia in the elderly and is a progressive neurodegenerative disorder characterised by a decline in cognitive function and also profound alterations in mood and behaviour.
The pathology of the disease is characterised by the presence of extracellular amyloid peptide deposits and intracellular neurofibrillary tangles in the brain.
Although many hypotheses have been put forward for the aetiology of the disease, increased inflammation and oxidative stress appear key to be features contributing to the pathology.
The omega-3 polyunsaturated fats, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) have well-characterised effects on inflammation and may have neuroprotective effects in a number of neurodegenerative conditions including Alzheimer's disease.
The aims of this paper are to review the neuroprotective effects of EPA and DHA in Alzheimer's disease, with special emphasis on their role in modulating oxidative stress and inflammation and also examine their potential as therapeutic agents.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dyall, S. C.. 2010. Amyloid-Beta Peptide, Oxidative Stress and Inflammation in Alzheimer's Disease : Potential Neuroprotective Effects of Omega-3 Polyunsaturated Fatty Acids. International Journal of Alzheimer's Disease،Vol. 2010, no. 2010, pp.1-10.
https://search.emarefa.net/detail/BIM-459436
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dyall, S. C.. Amyloid-Beta Peptide, Oxidative Stress and Inflammation in Alzheimer's Disease : Potential Neuroprotective Effects of Omega-3 Polyunsaturated Fatty Acids. International Journal of Alzheimer's Disease No. 2010 (2010), pp.1-10.
https://search.emarefa.net/detail/BIM-459436
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dyall, S. C.. Amyloid-Beta Peptide, Oxidative Stress and Inflammation in Alzheimer's Disease : Potential Neuroprotective Effects of Omega-3 Polyunsaturated Fatty Acids. International Journal of Alzheimer's Disease. 2010. Vol. 2010, no. 2010, pp.1-10.
https://search.emarefa.net/detail/BIM-459436
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-459436
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر