X-Ray Contrast Media Mechanisms in the Release of Mast Cell Contents : Understanding These Leads to a Treatment for Allergies

المؤلف

Lasser, Elliott C.

المصدر

Journal of Allergy

العدد

المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-5، 5ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2011-09-15

دولة النشر

مصر

عدد الصفحات

5

التخصصات الرئيسية

الطب البشري

الملخص EN

A long history of searching for the etiology of X-ray contrast material (CM) reactions has led to the understanding that the CM do not produce anti-CM antigens.

Since CM reactions are anaphylactoid in nature, however, a source for mast cell activation was sought.

This resulted in the finding that concentrated CM could suppress mast cell activation by attachment to the Fc portion of IgE and IgG.

This is presumed to be a steric hindrance effect.

In a study of the effects of CM on BP and a study of the effects of CM in sensitized rats, it was concluded that less concentrated CM activated mast cells and that this mechanism was best explained by bridging of adjacent IgE molecules via attachment to their Fc segments.

The mast cell release of heparin activating the contact system, as well as the release of histamine, is believed to be responsible for CM reactions and allergic diatheses.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Lasser, Elliott C.. 2011. X-Ray Contrast Media Mechanisms in the Release of Mast Cell Contents : Understanding These Leads to a Treatment for Allergies. Journal of Allergy،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-459631

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Lasser, Elliott C.. X-Ray Contrast Media Mechanisms in the Release of Mast Cell Contents : Understanding These Leads to a Treatment for Allergies. Journal of Allergy No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-459631

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Lasser, Elliott C.. X-Ray Contrast Media Mechanisms in the Release of Mast Cell Contents : Understanding These Leads to a Treatment for Allergies. Journal of Allergy. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-459631

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-459631