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Controlled Cohort Study of Serum Gonadal and Adrenocortical Steroid Levels in Males Prior to Onset of Rheumatoid Arthritis (pre-RA) : A Comparison to pre-RA Females and Sex Differences among the Study Groups
المؤلفون المشاركون
Chatterton, Robert T.
Wang, Huaping
Rehman, Azeem A.
Masi, Alfonse T.
Aldag, Jean C.
Goertzen, Ned J.
Elmore, Kevin B.
المصدر
International Journal of Rheumatology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-24
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Serum testosterone levels are generally reported to be lower in male rheumatoid arthritis (RA) patients, but it is not determined if a deficiency may occur before clinical onset of disease (pre-RA).
Lower testosterone levels were recently reported in males many years before RA onset but were predictive only of rheumatoid factor (RF)—negative disease.
A preceding prospective study did not reveal androgenic-anabolic hormone association with risk of RA in men or women.
This cohort study of males analyzed baseline serum levels of gonadal and adrenocortical steroids, luteinizing hormone, and prolactin in 18 pre-RA versus 72 matched non-RA control (CN) subjects.
Findings in males were compared to those in female pre-RA and CN subjects in the same cohort, and sex differences were analyzed.
Steroidal and hormonal levels, including total testosterone, were similar between male study groups.
In females, mean (±SE) serum androstenedione (nmol/L) was slightly (P=0.048) lower in 36 pre-RA (6.7 ± 0.36) than 144 CN (7.6 ± 0.22).
With the exception of 3 partial correlations of hormonal variables observed to differ between pre-RA versus CN subjects, the patterns were similar overall.
However, partial correlations of hormonal variables differed frequently by sex, both within and between study groups.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Masi, Alfonse T.& Rehman, Azeem A.& Chatterton, Robert T.& Wang, Huaping& Goertzen, Ned J.& Elmore, Kevin B.…[et al.]. 2013. Controlled Cohort Study of Serum Gonadal and Adrenocortical Steroid Levels in Males Prior to Onset of Rheumatoid Arthritis (pre-RA) : A Comparison to pre-RA Females and Sex Differences among the Study Groups. International Journal of Rheumatology،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-460254
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Masi, Alfonse T.…[et al.]. Controlled Cohort Study of Serum Gonadal and Adrenocortical Steroid Levels in Males Prior to Onset of Rheumatoid Arthritis (pre-RA) : A Comparison to pre-RA Females and Sex Differences among the Study Groups. International Journal of Rheumatology No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-460254
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Masi, Alfonse T.& Rehman, Azeem A.& Chatterton, Robert T.& Wang, Huaping& Goertzen, Ned J.& Elmore, Kevin B.…[et al.]. Controlled Cohort Study of Serum Gonadal and Adrenocortical Steroid Levels in Males Prior to Onset of Rheumatoid Arthritis (pre-RA) : A Comparison to pre-RA Females and Sex Differences among the Study Groups. International Journal of Rheumatology. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-460254
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460254
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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