Effect of Age-Related Cartilage Turnover on Serum C-Telopeptide of Collagen Type II and Osteocalcin Levels in Growing Rabbits with and without Surgically Induced Osteoarthritis
المؤلفون المشاركون
Ko, Sheung-Fat
Huang, Hsuan-Ying
Lee, Chen-Chang
Wang, Ching-Jen
Huang, Chung-Cheng
Tseng, Chia-Yi
Wang, Feng-Sheng
Ng, Shu-Hang
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-05
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
This study aims to determine the effect of age-related cartilage turnover on the serum C-telopeptide of type II collagen (CTX-II) and osteocalcin (OC) levels in growing rabbits with and without surgically induced osteoarthritis.
Twenty-four New Zealand male 3-month-old rabbits were randomized into three operated groups (n = 6 per group, with surgically induced osteroarthritis in the right knee; after blood sampling, the knees were harvested following euthanization at 2, 3, and 6 months after surgery) and a control group (n = 6, blood samples were obtained monthly between 3 and 15 months).
Histomorphologically, the medial femoral condyles, particularly the central parts, harbored the most severe osteoarthritic changes among the operated rabbits.
The serum levels of CTX-II and OC decreased in the controls from 3 to 11 months and then remained stable.
No significant differences in the serum CTX-II and OC levels between the osteoarthritic rabbits and controls were observed.
The osteoarthritic-to-normal ratios (ONRs, the ratios of serum CTX-II or OC levels in osteoarthritic rabbits to those of the controls at same ages) enabled an overall assessment of osteoarthritis and age-related cartilage turnover.
Elevated CTX-II ONRs were observed in rabbits with mild to advanced osteoarthritis.
However, the OC ONRs were unhelpful in assessing osteoarthritic growing rabbits.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Huang, Chung-Cheng& Lee, Chen-Chang& Wang, Ching-Jen& Wang, Feng-Sheng& Huang, Hsuan-Ying& Ng, Shu-Hang…[et al.]. 2014. Effect of Age-Related Cartilage Turnover on Serum C-Telopeptide of Collagen Type II and Osteocalcin Levels in Growing Rabbits with and without Surgically Induced Osteoarthritis. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-460313
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Huang, Chung-Cheng…[et al.]. Effect of Age-Related Cartilage Turnover on Serum C-Telopeptide of Collagen Type II and Osteocalcin Levels in Growing Rabbits with and without Surgically Induced Osteoarthritis. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-460313
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Huang, Chung-Cheng& Lee, Chen-Chang& Wang, Ching-Jen& Wang, Feng-Sheng& Huang, Hsuan-Ying& Ng, Shu-Hang…[et al.]. Effect of Age-Related Cartilage Turnover on Serum C-Telopeptide of Collagen Type II and Osteocalcin Levels in Growing Rabbits with and without Surgically Induced Osteoarthritis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-460313
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460313
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر