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Evaluation of Anti-Mutated Citrullinated Vimentin Antibodies, Anti-Cyclic Citrullinated Peptide Antibodies and Rheumatoid Factor in Omani Patients with Rheumatoid Arthritis
المؤلفون المشاركون
al-Ghafri, Saif
al-Marhoobi, Safia
Alkaabi, Juma
al-Shukaili, Ahmed
المصدر
International Journal of Rheumatology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-15
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Rheumatoid factor (RF) is currently used in the diagnosis of rheumatoid arthritis (RA).
The discovery of anticitrullinated protein autoantibodies has led to the development of various new tests, such as anti-cyclic citrullinated peptide (anti-CCP) antibodies, and anti-mutated citrullinated vimentin (anti-MCV) antibodies, to diagnose RA.
The aims of this study were to determine the sensitivity and specificity of anti-MCV antibodies in comparison with anti-CCP antibodies and RF in Omani Arab patients with RA and compare our findings with published values from different ethnic groups.
The sensitivity of anti-MCV antibodies was 72% with 87% specificity.
For anti-CCP antibodies the sensitivity was 52% and the specificity was 97%.
The sensitivity of RF was 57% with 94% specificity.
Anti-CCP antibodies have higher diagnostic specificity and positive predictive value than RF and anti-MCV antibodies.
Anti-MCV antibodies have the highest sensitivity when compared to anti-CCP antibodies and RF.
Anti-MCV antibodies do not appear to be very useful in the diagnosis of RA.
However, long-term study is required to find out whether anti-MCV antibodies can be used as predictive test for incidence of RA.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Shukaili, Ahmed& al-Ghafri, Saif& al-Marhoobi, Safia& Alkaabi, Juma. 2012. Evaluation of Anti-Mutated Citrullinated Vimentin Antibodies, Anti-Cyclic Citrullinated Peptide Antibodies and Rheumatoid Factor in Omani Patients with Rheumatoid Arthritis. International Journal of Rheumatology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-460417
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Shukaili, Ahmed…[et al.]. Evaluation of Anti-Mutated Citrullinated Vimentin Antibodies, Anti-Cyclic Citrullinated Peptide Antibodies and Rheumatoid Factor in Omani Patients with Rheumatoid Arthritis. International Journal of Rheumatology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-460417
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Shukaili, Ahmed& al-Ghafri, Saif& al-Marhoobi, Safia& Alkaabi, Juma. Evaluation of Anti-Mutated Citrullinated Vimentin Antibodies, Anti-Cyclic Citrullinated Peptide Antibodies and Rheumatoid Factor in Omani Patients with Rheumatoid Arthritis. International Journal of Rheumatology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-460417
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460417
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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