Sleep Deprivation Alters Rat Ventral Prostate Morphology, Leading to Glandular Atrophy : A Microscopic Study Contrasted with the Hormonal Assays

المؤلفون المشاركون

Taboga, Sebastião Roberto
Andersen, Monica L.
Vilamaior, Patricia S. L.
Tufik, Sergio
Venâncio, Daniel P.
Zager, Adriano
De Mello, Marco Túlio
Santos, Fernanda C.

المصدر

Journal of Biomedicine and Biotechnology

العدد

المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2012-08-08

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

الطب البشري

الملخص EN

We investigated the effect of 96 h paradoxical sleep deprivation (PSD) and 21-day sleep restriction (SR) on prostate morphology using stereological assays in male rats.

After euthanasia, the rat ventral prostate was removed, weighed, and prepared for conventional light microscopy.

Microscopic analysis of the prostate reveals that morphology of this gland was altered after 96 h of PSD and 21 days of SR, with the most important alterations occurring in the epithelium and stroma in the course of both procedures compared with the control group.

Both 96 h PSD and 21-day SR rats showed lower serum testosterone and higher corticosterone levels than control rats.

The significance of our result referring to the sleep deprivation was responsible for deep morphological alterations in ventral prostate tissue, like to castration microscopic modifications.

This result is due to the marked alterations in hormonal status caused by PSD and SR.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Venâncio, Daniel P.& Andersen, Monica L.& Vilamaior, Patricia S. L.& Santos, Fernanda C.& Zager, Adriano& Tufik, Sergio…[et al.]. 2012. Sleep Deprivation Alters Rat Ventral Prostate Morphology, Leading to Glandular Atrophy : A Microscopic Study Contrasted with the Hormonal Assays. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-460424

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Venâncio, Daniel P.…[et al.]. Sleep Deprivation Alters Rat Ventral Prostate Morphology, Leading to Glandular Atrophy : A Microscopic Study Contrasted with the Hormonal Assays. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-460424

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Venâncio, Daniel P.& Andersen, Monica L.& Vilamaior, Patricia S. L.& Santos, Fernanda C.& Zager, Adriano& Tufik, Sergio…[et al.]. Sleep Deprivation Alters Rat Ventral Prostate Morphology, Leading to Glandular Atrophy : A Microscopic Study Contrasted with the Hormonal Assays. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-460424

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-460424