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Exploring the Association between Retinal Nerve Fiber Layer Thickness and Initial Magnetic Resonance Imaging Findings in Patients with Acute Optic Neuritis
المؤلفون المشاركون
Hodge, William
Pan, Y. Irene
Costello, Fiona
المصدر
Multiple Sclerosis International
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-05-29
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Recent studies have shown that OCT-measured retinal nerve fiber layer (RNFL) values may represent a marker for axonal damage in the anterior visual pathway of optic neuritis (ON) and multiple sclerosis (MS) patients.
The goal of this study was to determine the link between RNFL values and initial magnetic resonance imaging (MRI) evidence of central nervous system (CNS) inflammation in patients with acute ON.
Methods.
Fifty patients who experienced ON as a clinically isolated syndrome (CIS) were followed for a mean period of 34 months with OCT testing.
RNFL values in affected (ON) eyes and clinically unaffected (non-ON) eyes were compared between patients with MRI evidence of white matter lesions and those with normal baseline MRI findings, over a two year period.
Findings.
Twenty-one patients (42%) developed clinically definite MS (CDMS) during the study.
After two years, temporal RNFL values were thinner (P=.07) in ON patients with MRI lesions at baseline, but the results were not significant.
Conclusions.
There is no association between RNFL values and baseline MRI status in ON patients at risk for future CDMS over a two year period.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Costello, Fiona& Hodge, William& Pan, Y. Irene. 2011. Exploring the Association between Retinal Nerve Fiber Layer Thickness and Initial Magnetic Resonance Imaging Findings in Patients with Acute Optic Neuritis. Multiple Sclerosis International،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-460699
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Costello, Fiona…[et al.]. Exploring the Association between Retinal Nerve Fiber Layer Thickness and Initial Magnetic Resonance Imaging Findings in Patients with Acute Optic Neuritis. Multiple Sclerosis International No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-460699
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Costello, Fiona& Hodge, William& Pan, Y. Irene. Exploring the Association between Retinal Nerve Fiber Layer Thickness and Initial Magnetic Resonance Imaging Findings in Patients with Acute Optic Neuritis. Multiple Sclerosis International. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-460699
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460699
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