The Relationship between Interleukin-18 Polymorphisms and Allergic Disease : A Meta-Analysis
المؤلفون المشاركون
Hao, Yiwen
Ma, Yiran
Cheng, Daye
Zhou, Wenling
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-05
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Recent studies have suggested that IL-18 −607C/A and −137G/C polymorphisms may be associated with the risk of allergic disease; however, individually published results are inconclusive.
Therefore, we performed a meta-analysis to clarify whether IL-18 −607C/A and −137G/C polymorphisms were associated with the risk of allergic disease.
A total of 21 studies including 5,331 cases and 9,658 controls were involved in this meta-analysis.
In the overall analysis and the subgroup analysis according to ethnicity, we did not find significant association between IL-18 −607C/A or −137G/C polymorphism and the risk of allergic disease (all P>0.05).
However, in a stratified analysis by type of allergic disease, our results indicated that IL-18 −607C/A polymorphism was associated with a significantly decreased risk of allergic asthma in heterozygous comparison and IL-18 −137G/C was associated with a significantly decreased risk of allergic dermatitis in recessive model and homozygous comparison.
In the stratified analysis by source of control, IL-18−607C/A showed significantly reduced risk in population-based subgroup, and for IL-18 −137G/C only significantly decreased risk was found in the hospital-based subgroup.
Our meta-analysis suggests that IL-18 −607C/A and −137G/C polymorphisms may be protective factors for the risk of allergic asthma and allergic dermatitis, respectively.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cheng, Daye& Hao, Yiwen& Zhou, Wenling& Ma, Yiran. 2014. The Relationship between Interleukin-18 Polymorphisms and Allergic Disease : A Meta-Analysis. BioMed Research International،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-460784
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cheng, Daye…[et al.]. The Relationship between Interleukin-18 Polymorphisms and Allergic Disease : A Meta-Analysis. BioMed Research International No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-460784
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cheng, Daye& Hao, Yiwen& Zhou, Wenling& Ma, Yiran. The Relationship between Interleukin-18 Polymorphisms and Allergic Disease : A Meta-Analysis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-460784
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460784
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر