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The Relationship between Interleukin-18 Polymorphisms and Allergic Disease : A Meta-Analysis
المؤلفون المشاركون
Hao, Yiwen
Ma, Yiran
Cheng, Daye
Zhou, Wenling
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-05
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Recent studies have suggested that IL-18 −607C/A and −137G/C polymorphisms may be associated with the risk of allergic disease; however, individually published results are inconclusive.
Therefore, we performed a meta-analysis to clarify whether IL-18 −607C/A and −137G/C polymorphisms were associated with the risk of allergic disease.
A total of 21 studies including 5,331 cases and 9,658 controls were involved in this meta-analysis.
In the overall analysis and the subgroup analysis according to ethnicity, we did not find significant association between IL-18 −607C/A or −137G/C polymorphism and the risk of allergic disease (all P>0.05).
However, in a stratified analysis by type of allergic disease, our results indicated that IL-18 −607C/A polymorphism was associated with a significantly decreased risk of allergic asthma in heterozygous comparison and IL-18 −137G/C was associated with a significantly decreased risk of allergic dermatitis in recessive model and homozygous comparison.
In the stratified analysis by source of control, IL-18−607C/A showed significantly reduced risk in population-based subgroup, and for IL-18 −137G/C only significantly decreased risk was found in the hospital-based subgroup.
Our meta-analysis suggests that IL-18 −607C/A and −137G/C polymorphisms may be protective factors for the risk of allergic asthma and allergic dermatitis, respectively.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cheng, Daye& Hao, Yiwen& Zhou, Wenling& Ma, Yiran. 2014. The Relationship between Interleukin-18 Polymorphisms and Allergic Disease : A Meta-Analysis. BioMed Research International،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-460784
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cheng, Daye…[et al.]. The Relationship between Interleukin-18 Polymorphisms and Allergic Disease : A Meta-Analysis. BioMed Research International No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-460784
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cheng, Daye& Hao, Yiwen& Zhou, Wenling& Ma, Yiran. The Relationship between Interleukin-18 Polymorphisms and Allergic Disease : A Meta-Analysis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-460784
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460784
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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