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Diagnosis of Latent Tuberculosis in Patients with Systemic Lupus Erythematosus : T.SPOT.TB versus Tuberculin Skin Test
المؤلفون المشاركون
Arenas Miras, Maria Del Mar
Jiménez-Alonso, Juan
Jimenez-Gamiz, Pilar
Hidalgo-Tenorio, Carmen
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-28
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Early studies in patients with systemic lupus erythematosus (SLE) reported increased incidence of tuberculosis.
The tuberculin skin test (TST) is the technique of choice to detect latent tuberculosis infection (LTBI) but has several limitations.
Objectives.
We compared TST and the newer T.SPOT.TB test to diagnose LTBI in SLE patients.
Methods.
In this observational cohort study conducted between August 2009 and February 2012, we recruited 92 patients from those attending the SLE clinic of our university hospital.
Data recorded were epidemiological and sociodemographic characteristics.
Laboratory analyses included TST and T.SPOT.TB tests.
Results.
Of the patients studied, 92% were women with an average age of 42.7 years.
Overall, the degree of correlation between the two tests was low (Kappa index = 0.324) but was better in patients not receiving corticosteroids (CTC)/immunosuppressive (IS) therapy (Kappa = 0.436) and in those receiving hydroxychloroquine (Kappa = 0.473).
While TST results were adversely affected by those receiving CTC and/or IS drugs (P=0.021), the T.SPOT.TB results were not.
Conclusion.
Although the TST test remains a useful tool for diagnosing LTBI in SLE patients, the T.SPOT.TB test is perhaps better employed when the patient is receiving CTC and/or IS drugs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Arenas Miras, Maria Del Mar& Hidalgo-Tenorio, Carmen& Jimenez-Gamiz, Pilar& Jiménez-Alonso, Juan. 2014. Diagnosis of Latent Tuberculosis in Patients with Systemic Lupus Erythematosus : T.SPOT.TB versus Tuberculin Skin Test. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-460828
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Arenas Miras, Maria Del Mar…[et al.]. Diagnosis of Latent Tuberculosis in Patients with Systemic Lupus Erythematosus : T.SPOT.TB versus Tuberculin Skin Test. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-460828
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Arenas Miras, Maria Del Mar& Hidalgo-Tenorio, Carmen& Jimenez-Gamiz, Pilar& Jiménez-Alonso, Juan. Diagnosis of Latent Tuberculosis in Patients with Systemic Lupus Erythematosus : T.SPOT.TB versus Tuberculin Skin Test. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-460828
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460828
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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