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Meta-Analysis of the Efficacy of Ectoine Nasal Spray in Patients with Allergic Rhinoconjunctivitis
المؤلفون المشاركون
Mösges, Ralph
Eichel, Andrea
Bilstein, Andreas
Werkhäuser, Nina
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-11
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Objectives.
The meta-analysis aims to investigate the efficacy of ectoine nasal spray and eye drops in the treatment of allergic rhinitis and rhinoconjunctivitis symptoms.
Design and Methods.
This meta-analysis is based on yet unpublished data of four studies.
Both nasal and eye symptoms were documented in patient diary cards.
All scales were transformed into a 4-point scale: 0 = no, 1 = mild, 2 = moderate, and 3 = severe symptoms.
Each symptom was analysed individually in a meta-analysis of the area under the curve values as well as in a meta-analysis of pre- and posttreatment comparison.
Results.
After seven days of treatment with ectoine nasal spray both nasal and ocular symptoms decreased significantly.
A strong reduction of symptom severity was shown for the parameters rhinorrhoea (31.76% reduction) and nasal obstruction (29.94% reduction).
Furthermore, the meta-analyses of individual symptoms to investigate the strength of effect after seven days of medication intake showed significant improvement for nasal obstruction, rhinorrhoea, nasal itching, sneezing, itching of eyes, and redness of eyes.
The improvement of the symptom nasal obstruction was associated with a strong effect 0.53 (±0.26).
Conclusions.
The ectoine nasal spray and eye drops seem to be equally effective as guideline-recommended medication in the treatment of rhinoconjunctivitis symptoms.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Eichel, Andrea& Bilstein, Andreas& Werkhäuser, Nina& Mösges, Ralph. 2014. Meta-Analysis of the Efficacy of Ectoine Nasal Spray in Patients with Allergic Rhinoconjunctivitis. Journal of Allergy،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-460973
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Eichel, Andrea…[et al.]. Meta-Analysis of the Efficacy of Ectoine Nasal Spray in Patients with Allergic Rhinoconjunctivitis. Journal of Allergy No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-460973
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Eichel, Andrea& Bilstein, Andreas& Werkhäuser, Nina& Mösges, Ralph. Meta-Analysis of the Efficacy of Ectoine Nasal Spray in Patients with Allergic Rhinoconjunctivitis. Journal of Allergy. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-460973
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460973
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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