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Efficacy and Safety of Duloxetine in Patients with Chronic Low Back Pain Who Used versus Did Not Use Concomitant Nonsteroidal Anti-Inflammatory Drugs or Acetaminophen : A Post Hoc Pooled Analysis of 2 Randomized, Placebo-Controlled Trials
المؤلفون المشاركون
Ahl, Jonna
Zhang, Shuyu
Skljarevski, Vladimir
Martinez, James M.
Liu, Peng
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-03-18
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
This subgroup analysis assessed the efficacy of duloxetine in patients with chronic low back pain (CLBP) who did or did not use concomitant nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen (APAP).
Data were pooled from two 13-week randomized trials in patients with CLBP who were stratified according to NSAID/APAP use at baseline: duloxetine NSAID/APAP user (n=137), placebo NSAID/APAP user (n=82), duloxetine NSAID/APAP nonuser (n=206), and placebo NSAID/APAP nonuser (n=156).
NSAID/APAP users were those patients who took NSAID/APAP for at least 14 days per month during 3 months prior to study entry.
An analysis of covariance model that included therapy, study, baseline NSAID/APAP use (yes/no), and therapy-by-NSAID/APAP subgroup interaction was used to assess the efficacy.
The treatment-by-NSAID/APAP use interaction was not statistically significant (P=0.31) suggesting no substantial evidence of differential efficacy for duloxetine over placebo on pain reduction or improvement in physical function between concomitant NSAID/APAP users and non-users.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Skljarevski, Vladimir& Liu, Peng& Zhang, Shuyu& Ahl, Jonna& Martinez, James M.. 2012. Efficacy and Safety of Duloxetine in Patients with Chronic Low Back Pain Who Used versus Did Not Use Concomitant Nonsteroidal Anti-Inflammatory Drugs or Acetaminophen : A Post Hoc Pooled Analysis of 2 Randomized, Placebo-Controlled Trials. Pain Research and Treatment،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-461341
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Skljarevski, Vladimir…[et al.]. Efficacy and Safety of Duloxetine in Patients with Chronic Low Back Pain Who Used versus Did Not Use Concomitant Nonsteroidal Anti-Inflammatory Drugs or Acetaminophen : A Post Hoc Pooled Analysis of 2 Randomized, Placebo-Controlled Trials. Pain Research and Treatment No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-461341
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Skljarevski, Vladimir& Liu, Peng& Zhang, Shuyu& Ahl, Jonna& Martinez, James M.. Efficacy and Safety of Duloxetine in Patients with Chronic Low Back Pain Who Used versus Did Not Use Concomitant Nonsteroidal Anti-Inflammatory Drugs or Acetaminophen : A Post Hoc Pooled Analysis of 2 Randomized, Placebo-Controlled Trials. Pain Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-461341
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-461341
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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