Efficacy and Safety of Duloxetine in Patients with Chronic Low Back Pain Who Used versus Did Not Use Concomitant Nonsteroidal Anti-Inflammatory Drugs or Acetaminophen : A Post Hoc Pooled Analysis of 2 Randomized, Placebo-Controlled Trials
المؤلفون المشاركون
Ahl, Jonna
Zhang, Shuyu
Skljarevski, Vladimir
Martinez, James M.
Liu, Peng
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-03-18
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
This subgroup analysis assessed the efficacy of duloxetine in patients with chronic low back pain (CLBP) who did or did not use concomitant nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen (APAP).
Data were pooled from two 13-week randomized trials in patients with CLBP who were stratified according to NSAID/APAP use at baseline: duloxetine NSAID/APAP user (n=137), placebo NSAID/APAP user (n=82), duloxetine NSAID/APAP nonuser (n=206), and placebo NSAID/APAP nonuser (n=156).
NSAID/APAP users were those patients who took NSAID/APAP for at least 14 days per month during 3 months prior to study entry.
An analysis of covariance model that included therapy, study, baseline NSAID/APAP use (yes/no), and therapy-by-NSAID/APAP subgroup interaction was used to assess the efficacy.
The treatment-by-NSAID/APAP use interaction was not statistically significant (P=0.31) suggesting no substantial evidence of differential efficacy for duloxetine over placebo on pain reduction or improvement in physical function between concomitant NSAID/APAP users and non-users.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Skljarevski, Vladimir& Liu, Peng& Zhang, Shuyu& Ahl, Jonna& Martinez, James M.. 2012. Efficacy and Safety of Duloxetine in Patients with Chronic Low Back Pain Who Used versus Did Not Use Concomitant Nonsteroidal Anti-Inflammatory Drugs or Acetaminophen : A Post Hoc Pooled Analysis of 2 Randomized, Placebo-Controlled Trials. Pain Research and Treatment،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-461341
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Skljarevski, Vladimir…[et al.]. Efficacy and Safety of Duloxetine in Patients with Chronic Low Back Pain Who Used versus Did Not Use Concomitant Nonsteroidal Anti-Inflammatory Drugs or Acetaminophen : A Post Hoc Pooled Analysis of 2 Randomized, Placebo-Controlled Trials. Pain Research and Treatment No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-461341
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Skljarevski, Vladimir& Liu, Peng& Zhang, Shuyu& Ahl, Jonna& Martinez, James M.. Efficacy and Safety of Duloxetine in Patients with Chronic Low Back Pain Who Used versus Did Not Use Concomitant Nonsteroidal Anti-Inflammatory Drugs or Acetaminophen : A Post Hoc Pooled Analysis of 2 Randomized, Placebo-Controlled Trials. Pain Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-461341
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-461341
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر