Morphological Effects of HA on the Cell Compatibility of Electrospun HAPLGA Composite Nanofiber Scaffolds
المؤلفون المشاركون
Haider, Adnan
Kang, Inn-Kyu
Gupta, Kailash Chandra
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-26
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Tissue engineering is faced with an uphill challenge to design a platform with appropriate topography and suitable surface chemistry, which could encourage desired cellular activities and guide bone tissue regeneration.
To develop such scaffolds, composite nanofiber scaffolds of nHA and sHA with PLGA were fabricated using electrospinning technique.
nHA was synthesized using precipitation method, whereas sHA was purchased.
The nHA and sHA were suspended in PLGA solution separately and electrospun at optimized electrospinning parameters.
The composite nanofiber scaffolds were characterized by FE-SEM, EDX analysis, TEM, XRD analysis, FTIR, and X-ray photoelectron.
The potential of the HA/PLGA composite nanofiber as bone scaffolds in terms of their bioactivity and biocompatibility was assessed by culturing the osteoblastic cells onto the composite nanofiber scaffolds.
The results from in vitro studies revealed that the nHA/PLGA composite nanofiber scaffolds showed higher cellular adhesion, proliferation, and enhanced osteogenesis performance, along with increased Ca+2 ions release compared to the sHA/PLGA composite nanofiber scaffolds and pristine PLGA nanofiber scaffold.
The results show that the structural dependent property of HA might affect its potential as bone scaffold and implantable materials in regenerative medicine and clinical tissue engineering.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Haider, Adnan& Gupta, Kailash Chandra& Kang, Inn-Kyu. 2014. Morphological Effects of HA on the Cell Compatibility of Electrospun HAPLGA Composite Nanofiber Scaffolds. BioMed Research International،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-462250
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Haider, Adnan…[et al.]. Morphological Effects of HA on the Cell Compatibility of Electrospun HAPLGA Composite Nanofiber Scaffolds. BioMed Research International No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-462250
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Haider, Adnan& Gupta, Kailash Chandra& Kang, Inn-Kyu. Morphological Effects of HA on the Cell Compatibility of Electrospun HAPLGA Composite Nanofiber Scaffolds. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-462250
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-462250
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر