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In Vivo Effects of Cagaita (Eugenia dysenterica, DC.) Leaf Extracts on Diarrhea Treatment
المؤلفون المشاركون
Lima, T. B.
Grossi-de-Sa, Maria Fátima
Silva, Luciano Paulino
Leonardecz, E.
Rocha, Thales Lima
Franco, Octavio L.
Silva, Osmar Nascimento
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-08-30
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Eugenia dysenterica is a plant typically found in the Cerrado biome and commonly used in popular medicine due to its pharmacological properties, which include antidiarrheal, skin healing, and antimicrobial activities.
The effects of ethanolic extract, aqueous extract and infusion of E.
dysenterica leaves on intestinal motility and antidiarrheal activity were evaluated using ricin oil-induced diarrhea in rats.
At doses of 400 and 800 mg⋅Kg−1, the ethanolic extract decreased intestinal motility while the other extracts showed no significant effects.
Moreover, serum levels of chloride, magnesium, and phosphorus were also measured in rats.
Histopathologic and enzymatic analyses were also performed to investigate any toxic effect.
Animals treated with infusion, ethanolic extract, ricin oil, and loperamide presented morphological alterations in the small intestine, such as mucosa lesion, epithelial layer damage, and partial loss and/or morphological change of villi.
Furthermore, the liver showed congestion and hydropic degeneration.
Serum levels of alanine aminotransferase increased significantly in all treatments, but none rose above reference values.
In summary, our results suggest that compounds present in leaves of E.
dysenterica may have therapeutic benefits on recovery from diarrhea despite their toxic effects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lima, T. B.& Silva, Osmar Nascimento& Silva, Luciano Paulino& Rocha, Thales Lima& Grossi-de-Sa, Maria Fátima& Franco, Octavio L.…[et al.]. 2010. In Vivo Effects of Cagaita (Eugenia dysenterica, DC.) Leaf Extracts on Diarrhea Treatment. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-462366
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lima, T. B.…[et al.]. In Vivo Effects of Cagaita (Eugenia dysenterica, DC.) Leaf Extracts on Diarrhea Treatment. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-462366
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lima, T. B.& Silva, Osmar Nascimento& Silva, Luciano Paulino& Rocha, Thales Lima& Grossi-de-Sa, Maria Fátima& Franco, Octavio L.…[et al.]. In Vivo Effects of Cagaita (Eugenia dysenterica, DC.) Leaf Extracts on Diarrhea Treatment. Evidence-Based Complementary and Alternative Medicine. 2010. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-462366
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-462366
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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