Cholestatic Hepatitis with Small Duct Injury Associated with Celecoxib

المؤلفون المشاركون

Badipatla, Shanti
Niazi, Masooma
Balar, Bhavna
Nayudu, Suresh Kumar

المصدر

Case Reports in Medicine

العدد

المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-3، 3ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2013-06-05

دولة النشر

مصر

عدد الصفحات

3

التخصصات الرئيسية

الطب البشري

الملخص EN

Drug-induced liver injury (DILI) is a common clinical entity but is underreported due to various reasons.

Cyclooxygenase-2 inhibitors like Celecoxib have been proven to be associated with lesser incidence of adverse drug reactions compared to other nonsteroidal anti-inflammatory drugs (NSAID).

However, Celecoxib has been rarely reported to be associated with cholestasis and hepatitis.

We present a young Hispanic female presented with cholestatic liver chemistries who has been taking Celecoxib for 3 weeks.

Extensive workup did not support diagnosis of viral, autoimmune, or metabolic liver diseases.

Liver biopsy revealed findings suggestive of secondary sclerosing cholangitis.

Imaging studies were negative for large duct involvement, and endoscopy ruled out inflammatory bowel disease.

Liver chemistries normalized after cessation of medication.

We recommend that physician should be aware of this rare complication when prescribing Celecoxib.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Nayudu, Suresh Kumar& Badipatla, Shanti& Niazi, Masooma& Balar, Bhavna. 2013. Cholestatic Hepatitis with Small Duct Injury Associated with Celecoxib. Case Reports in Medicine،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-462817

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Nayudu, Suresh Kumar…[et al.]. Cholestatic Hepatitis with Small Duct Injury Associated with Celecoxib. Case Reports in Medicine No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-462817

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Nayudu, Suresh Kumar& Badipatla, Shanti& Niazi, Masooma& Balar, Bhavna. Cholestatic Hepatitis with Small Duct Injury Associated with Celecoxib. Case Reports in Medicine. 2013. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-462817

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-462817