The Impacts of Along-Channel Acupuncture on the Protein Expressions of the Chloride Channel of the Rats with Myocardial Ischemia

المؤلفون المشاركون

Li, Yuan
Zhang, Xiao-Qing
Liang, Fan-Rong
Cheng, Ze-Dong
Li, Chun-Ri
Chen, Yi-Guo
Rong, Pei-Jing
Shao, Xiao-Jiao

المصدر

Evidence-Based Complementary and Alternative Medicine

العدد

المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2013-06-24

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

الطب البشري

الملخص EN

Recent evidence suggests that chloride (CL−) channels are involved in myocardial ischemia.

In this study, the impact of acupuncture on the protein expressions of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and CLC-2 CL− channel of the rats with myocardial ischemia were tested and its mechanism was explored.

The rats for experiment were distributed randomly into 5 groups: blank control group, modeling control group, Neiguan (PC-6) treatment group, Lieque (LU-7) control group, and Non-acupoint control group.

The rats of all groups, except the blank control group, had myocardial ischemia via multiple subcutaneous injection of isoproterenol (ISO).

Electroacupuncture treatment was given to Neiguan (PC-6) treatment group, Lieque (LU-7) control group, and Non-acupoints control group, respectively, once a day for 7 days.

The results show that acupuncture can alleviate the myocardial ischemia of cardiac tissue, decrease significantly the activities of serum SOD and MDA, and thereby influence the protein expressions of CFTR and CLC-2 in CL− channels.

The results of the study implies that acupuncture suppresses the pathological changes of cardiac tissue of rats with myocardial ischemia and regulates the protein expression of CFTR and CLC-2 CL− channels, which may serve as one possible mechanism to reduce myocardial ischemia.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Cheng, Ze-Dong& Li, Chun-Ri& Shao, Xiao-Jiao& Rong, Pei-Jing& Zhang, Xiao-Qing& Liang, Fan-Rong…[et al.]. 2013. The Impacts of Along-Channel Acupuncture on the Protein Expressions of the Chloride Channel of the Rats with Myocardial Ischemia. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-463330

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Cheng, Ze-Dong…[et al.]. The Impacts of Along-Channel Acupuncture on the Protein Expressions of the Chloride Channel of the Rats with Myocardial Ischemia. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-463330

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Cheng, Ze-Dong& Li, Chun-Ri& Shao, Xiao-Jiao& Rong, Pei-Jing& Zhang, Xiao-Qing& Liang, Fan-Rong…[et al.]. The Impacts of Along-Channel Acupuncture on the Protein Expressions of the Chloride Channel of the Rats with Myocardial Ischemia. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-463330

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-463330