The Impacts of Along-Channel Acupuncture on the Protein Expressions of the Chloride Channel of the Rats with Myocardial Ischemia
Joint Authors
Li, Yuan
Zhang, Xiao-Qing
Liang, Fan-Rong
Cheng, Ze-Dong
Li, Chun-Ri
Chen, Yi-Guo
Rong, Pei-Jing
Shao, Xiao-Jiao
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-24
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Recent evidence suggests that chloride (CL−) channels are involved in myocardial ischemia.
In this study, the impact of acupuncture on the protein expressions of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and CLC-2 CL− channel of the rats with myocardial ischemia were tested and its mechanism was explored.
The rats for experiment were distributed randomly into 5 groups: blank control group, modeling control group, Neiguan (PC-6) treatment group, Lieque (LU-7) control group, and Non-acupoint control group.
The rats of all groups, except the blank control group, had myocardial ischemia via multiple subcutaneous injection of isoproterenol (ISO).
Electroacupuncture treatment was given to Neiguan (PC-6) treatment group, Lieque (LU-7) control group, and Non-acupoints control group, respectively, once a day for 7 days.
The results show that acupuncture can alleviate the myocardial ischemia of cardiac tissue, decrease significantly the activities of serum SOD and MDA, and thereby influence the protein expressions of CFTR and CLC-2 in CL− channels.
The results of the study implies that acupuncture suppresses the pathological changes of cardiac tissue of rats with myocardial ischemia and regulates the protein expression of CFTR and CLC-2 CL− channels, which may serve as one possible mechanism to reduce myocardial ischemia.
American Psychological Association (APA)
Cheng, Ze-Dong& Li, Chun-Ri& Shao, Xiao-Jiao& Rong, Pei-Jing& Zhang, Xiao-Qing& Liang, Fan-Rong…[et al.]. 2013. The Impacts of Along-Channel Acupuncture on the Protein Expressions of the Chloride Channel of the Rats with Myocardial Ischemia. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-463330
Modern Language Association (MLA)
Cheng, Ze-Dong…[et al.]. The Impacts of Along-Channel Acupuncture on the Protein Expressions of the Chloride Channel of the Rats with Myocardial Ischemia. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-463330
American Medical Association (AMA)
Cheng, Ze-Dong& Li, Chun-Ri& Shao, Xiao-Jiao& Rong, Pei-Jing& Zhang, Xiao-Qing& Liang, Fan-Rong…[et al.]. The Impacts of Along-Channel Acupuncture on the Protein Expressions of the Chloride Channel of the Rats with Myocardial Ischemia. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-463330
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463330