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PET Imaging in Recurrent Medullary Thyroid Carcinoma
المؤلفون المشاركون
Treglia, Giorgio
Giordano, Alessandro
Giovanella, Luca
Rufini, Vittoria
Salvatori, Massimo
المصدر
International Journal of Molecular Imaging
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-07-18
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Purpose.
To perform an overview about the role of positron emission tomography (PET) or PET/computed tomography (PET/CT) using different radiopharmaceuticals in recurrent medullary thyroid carcinoma (MTC) based on biochemical findings (increased tumor marker levels after primary surgery).
Methods.
A comprehensive literature search of studies published in PubMed/MEDLINE, Scopus, and Embase databases through February 2012 regarding PET or PET/CT in patients with recurrent MTC was performed.
Results.
Twenty-nine studies comprising 714 patients with suspected recurrent MTC were retrieved.
Twenty-seven articles evaluated the role of fluorine-18-fluorodeoxyglucose (FDG) PET or PET/CT in recurrent MTC with conflicting results.
Diagnostic accuracy of FDG-PET and PET/CT increased in MTC patients with higher calcitonin and carcinoembryonic antigen values, suggesting that these imaging methods could be very useful in patients with more advanced and aggressive disease.
Eight articles evaluated the role of fluorine-18-dihydroxyphenylalanine (FDOPA) PET or PET/CT in recurrent MTC reporting promising results.
Overall, FDOPA seems to be superior but complementary compared to FDG in detecting recurrent MTC.
Few studies evaluating other PET tracers are also discussed.
Conclusions.
PET radiopharmaceuticals reflect different metabolic pathways in MTC.
FDOPA seems to be the most useful PET tracer in detecting recurrent MTC based on rising levels of tumor markers.
FDG may complement FDOPA in patients with more aggressive MTC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Treglia, Giorgio& Rufini, Vittoria& Salvatori, Massimo& Giordano, Alessandro& Giovanella, Luca. 2012. PET Imaging in Recurrent Medullary Thyroid Carcinoma. International Journal of Molecular Imaging،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-463562
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Treglia, Giorgio…[et al.]. PET Imaging in Recurrent Medullary Thyroid Carcinoma. International Journal of Molecular Imaging No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-463562
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Treglia, Giorgio& Rufini, Vittoria& Salvatori, Massimo& Giordano, Alessandro& Giovanella, Luca. PET Imaging in Recurrent Medullary Thyroid Carcinoma. International Journal of Molecular Imaging. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-463562
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-463562
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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