The Role of Simvastatin in the Therapeutic Approach of Rheumatoid Arthritis

المؤلفون المشاركون

Rusali, Andrei Constantin
Şuţa, Maria
Rădulescu, Anca Mihaela
Şuţa, Cristina
Cojocaru, Lucia
Craiu, Elvira

المصدر

Autoimmune Diseases

العدد

المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2013-06-12

دولة النشر

مصر

عدد الصفحات

7

التخصصات الرئيسية

الأمراض

الملخص EN

The pleiotropic effects of statins, especially the anti-inflammatory and immunomodulatory ones, indicate that their therapeutic potential might extend beyond cholesterol lowering and cardiovascular disease to other inflammatory disorders such as rheumatoid arthritis.

Therefore, we undertook a prospective cohort study to evaluate the efficacy and safety of simvastatin used for inflammation control in patients with rheumatoid arthritis.

One hundred patients with active rheumatoid arthritis divided into two equal groups (the study one who received 20 mg/day of simvastatin in addition to prior DMARDs and the control one) were followed up over six months during three study visits.

The results of the study support the fact that simvastatin at a dose of 20 mg/day has a low anti-inflammatory effect in patients with rheumatoid arthritis with a good safety profile.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Cojocaru, Lucia& Rusali, Andrei Constantin& Şuţa, Cristina& Rădulescu, Anca Mihaela& Şuţa, Maria& Craiu, Elvira. 2013. The Role of Simvastatin in the Therapeutic Approach of Rheumatoid Arthritis. Autoimmune Diseases،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-463718

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Cojocaru, Lucia…[et al.]. The Role of Simvastatin in the Therapeutic Approach of Rheumatoid Arthritis. Autoimmune Diseases No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-463718

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Cojocaru, Lucia& Rusali, Andrei Constantin& Şuţa, Cristina& Rădulescu, Anca Mihaela& Şuţa, Maria& Craiu, Elvira. The Role of Simvastatin in the Therapeutic Approach of Rheumatoid Arthritis. Autoimmune Diseases. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-463718

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-463718