The Role of Simvastatin in the Therapeutic Approach of Rheumatoid Arthritis
Joint Authors
Rusali, Andrei Constantin
Şuţa, Maria
Rădulescu, Anca Mihaela
Şuţa, Cristina
Cojocaru, Lucia
Craiu, Elvira
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-12
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The pleiotropic effects of statins, especially the anti-inflammatory and immunomodulatory ones, indicate that their therapeutic potential might extend beyond cholesterol lowering and cardiovascular disease to other inflammatory disorders such as rheumatoid arthritis.
Therefore, we undertook a prospective cohort study to evaluate the efficacy and safety of simvastatin used for inflammation control in patients with rheumatoid arthritis.
One hundred patients with active rheumatoid arthritis divided into two equal groups (the study one who received 20 mg/day of simvastatin in addition to prior DMARDs and the control one) were followed up over six months during three study visits.
The results of the study support the fact that simvastatin at a dose of 20 mg/day has a low anti-inflammatory effect in patients with rheumatoid arthritis with a good safety profile.
American Psychological Association (APA)
Cojocaru, Lucia& Rusali, Andrei Constantin& Şuţa, Cristina& Rădulescu, Anca Mihaela& Şuţa, Maria& Craiu, Elvira. 2013. The Role of Simvastatin in the Therapeutic Approach of Rheumatoid Arthritis. Autoimmune Diseases،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-463718
Modern Language Association (MLA)
Cojocaru, Lucia…[et al.]. The Role of Simvastatin in the Therapeutic Approach of Rheumatoid Arthritis. Autoimmune Diseases No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-463718
American Medical Association (AMA)
Cojocaru, Lucia& Rusali, Andrei Constantin& Şuţa, Cristina& Rădulescu, Anca Mihaela& Şuţa, Maria& Craiu, Elvira. The Role of Simvastatin in the Therapeutic Approach of Rheumatoid Arthritis. Autoimmune Diseases. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-463718
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-463718