Antioxidant Action of Mangrove Polyphenols against Gastric Damage Induced by Absolute Ethanol and Ischemia-Reperfusion in the Rat

المؤلفون المشاركون

Vilegas, Wagner
Almeida, Ana Cristina Alves
Toma, Walber
da Silva, Marcelo Aparecido
Abdelnur, Patrícia Verardi
Luiz-Ferreira, Anderson
Salvador, Marcos José
Takayama, Christiane
Eberlin, Marcos Nogueira
de-Faria, Felipe Meira
Dunder, Ricardo José
Souza-Brito, Alba Regina Monteiro

المصدر

The Scientific World Journal

العدد

المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2012-04-30

دولة النشر

مصر

عدد الصفحات

9

التخصصات الرئيسية

العلوم الطبيعية والحياتية (متداخلة التخصصات)
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب

الملخص EN

Rhizophora mangle, the red mangrove, has long been known as a traditional medicine.

Its bark has been used as astringent, antiseptic, hemostatic, with antifungic and antiulcerogenic properties.

In this paper, we aimed to evaluate the antioxidant properties of a buthanolic fraction of the R.

mangle bark extract (RM) against experimental gastric ulcer in rats.

Unib-Wh rats received pretreatment of R.

mangle after the induction of gastric injury with absolute ethanol and ischemia-reperfusion.

Gastric tissues from both methods were prepared to the enzymatic assays, the levels of sulfhydril compounds (GSH), lipid peroxides (LPO), and the activities of glutathione reductase (GR), glutathione peroxidase (GPx), superoxide dismutase (SOD) and myeloperoxidase (MPO) were measured.

The RM protected the gastric mucosa in both methods used, ethanol-induced gastric ulcer and ischemia-reperfusion, probably, by modulating the activities of the enzymes SOD, GPx, and GR and increasing or maintaining the levels of GSH; in adittion, LPO levels were reduced.

The results suggest that the RM antioxidant activity leads to tissue protection; thus one of the antiulcer mechanisms present on the pharmacological effects of R.

mangle is the antioxidant property.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

de-Faria, Felipe Meira& Almeida, Ana Cristina Alves& Luiz-Ferreira, Anderson& Takayama, Christiane& Dunder, Ricardo José& da Silva, Marcelo Aparecido…[et al.]. 2012. Antioxidant Action of Mangrove Polyphenols against Gastric Damage Induced by Absolute Ethanol and Ischemia-Reperfusion in the Rat. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-463789

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

de-Faria, Felipe Meira…[et al.]. Antioxidant Action of Mangrove Polyphenols against Gastric Damage Induced by Absolute Ethanol and Ischemia-Reperfusion in the Rat. The Scientific World Journal No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-463789

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

de-Faria, Felipe Meira& Almeida, Ana Cristina Alves& Luiz-Ferreira, Anderson& Takayama, Christiane& Dunder, Ricardo José& da Silva, Marcelo Aparecido…[et al.]. Antioxidant Action of Mangrove Polyphenols against Gastric Damage Induced by Absolute Ethanol and Ischemia-Reperfusion in the Rat. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-463789

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-463789