![](/images/graphics-bg.png)
Cigarette Smoking Is Associated with Prolongation of the QTc Interval Duration in Patients with Type 2 Diabetes Mellitus
المؤلفون المشاركون
Makrilakis, Konstantinos
Vlahodimitris, Ioannis
Liatis, Stavros
Stathi, Chryssoula
Katsilambros, Nicholas L.
Kalopita, Stavroula
Thomakos, Petros
Tentolouris, Nicholas
المصدر
International Journal of Endocrinology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-04-24
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Aims.
Aim of the study was to evaluate the effect of smoking on autonomic nervous system (ANS) activity and QTc interval duration in patients with Type 2 diabetes mellitus (T2DM).
Methods.
A total of 70 patients with T2DM (35 chronic smokers, 35 nonsmokers) treated with oral antidiabetic medications underwent continuous ECG Holter monitoring for 24 hours and analysis of time- and frequency-domain measures of heart rate variability (HRV).
HRV over short time was also assessed using the deep breathing test.
In addition, baroreflex sensitivity (BRS) was evaluated using the spontaneous sequence method.
The mean QTc interval was measured from the 24-hour ECG recordings.
Results.
Smokers had lower body mass index (BMI) and exhibited higher 24-hour mean heart rate.
There was no difference regarding all measures of ANS activity between the two groups.
Smokers showed increased mean QTc duration during the 24 hours (439.25±26.95 versus 425.05±23.03 ms, P=0.021) as well as in both day (439.14±24.31 ms, P=0.042) and night periods (440.91±32.30 versus 425.51±24.98 ms, P=0.033).
The association between smoking status and mean QTc interval persisted after adjusting for BMI.
Conclusions.
Cigarette smoking is associated with prolongation of the QTc interval in patients with T2DM by a mechanism independent of ANS dysfunction.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Thomakos, Petros& Liatis, Stavros& Kalopita, Stavroula& Vlahodimitris, Ioannis& Stathi, Chryssoula& Katsilambros, Nicholas L.…[et al.]. 2013. Cigarette Smoking Is Associated with Prolongation of the QTc Interval Duration in Patients with Type 2 Diabetes Mellitus. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-463993
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Thomakos, Petros…[et al.]. Cigarette Smoking Is Associated with Prolongation of the QTc Interval Duration in Patients with Type 2 Diabetes Mellitus. International Journal of Endocrinology No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-463993
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Thomakos, Petros& Liatis, Stavros& Kalopita, Stavroula& Vlahodimitris, Ioannis& Stathi, Chryssoula& Katsilambros, Nicholas L.…[et al.]. Cigarette Smoking Is Associated with Prolongation of the QTc Interval Duration in Patients with Type 2 Diabetes Mellitus. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-463993
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-463993
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)