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An International, Web-Based, Prospective Cohort Study to Determine Whether the Use of ACE Inhibitors prior to the Onset of Scleroderma Renal Crisis Is Associated with Worse Outcomes—Methodology and Preliminary Results
المؤلفون المشاركون
Khanna, Dinesh
Baron, Murray
Lo, Ernest
Hudson, Marie
Weinfeld, Joanna
Furst, Daniel E.
المصدر
International Journal of Rheumatology
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-09-14
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
To describe the methodology of a study designed to determine whether systemic sclerosis (SSc) patients with incident scleroderma renal crisis (SRC) on angiotensin converting enzyme (ACE) inhibitors prior to the onset of SRC have worse outcomes.
Methods.
Prospective, international cohort study of SRC subjects identified through an ongoing web-based survey.
Every second Friday afternoon, an e-mail was sent to 589 participating physicians to identify new cases of SRC.
Death or dialysis at one year after the onset of SRC will be compared in patients exposed or not to ACE inhibitors prior to the onset of SRC.
Results.
Fifteen months after the start of the survey, we had identified 76 incident cases of SRC.
Of these, 66 (87%) had a hypertensive SRC and 10 (13%) a normotensive SRC.
Twenty-two percent (22%) of the patients were on an ACE inhibitor immediately prior to the onset of the SRC.
To date, we have collected one-year follow-up data on approximately 1/3 of the cohort.
Of these, over 50% have died or remain on dialysis at one year.
Conclusion.
An international, web-based cohort study design is a feasible method of recruiting a substantial number of patients to study an infrequent vascular manifestation of SSc.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hudson, Marie& Baron, Murray& Lo, Ernest& Weinfeld, Joanna& Furst, Daniel E.& Khanna, Dinesh. 2010. An International, Web-Based, Prospective Cohort Study to Determine Whether the Use of ACE Inhibitors prior to the Onset of Scleroderma Renal Crisis Is Associated with Worse Outcomes—Methodology and Preliminary Results. International Journal of Rheumatology،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-464644
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hudson, Marie…[et al.]. An International, Web-Based, Prospective Cohort Study to Determine Whether the Use of ACE Inhibitors prior to the Onset of Scleroderma Renal Crisis Is Associated with Worse Outcomes—Methodology and Preliminary Results. International Journal of Rheumatology No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-464644
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hudson, Marie& Baron, Murray& Lo, Ernest& Weinfeld, Joanna& Furst, Daniel E.& Khanna, Dinesh. An International, Web-Based, Prospective Cohort Study to Determine Whether the Use of ACE Inhibitors prior to the Onset of Scleroderma Renal Crisis Is Associated with Worse Outcomes—Methodology and Preliminary Results. International Journal of Rheumatology. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-464644
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-464644
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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