Synthetic Methods, Chemistry, and the Anticonvulsant Activity of Thiadiazoles
المؤلفون المشاركون
Sharma, Upendra Kumar
Sharma, Bhawna
Verma, Amita
Prajapati, Sunil
المصدر
International Journal of Medicinal Chemistry
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-04-30
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
The chemistry of heterocyclic compounds has been an interesting field of study for a long time.
Heterocyclic nucleus 1,3,4-thiadiazole constitutes an important class of compounds for new drug development.
The synthesis of novel thiadiazole derivatives and investigation of their chemical and biological behavior have gained more importance in recent decades.
The search for antiepileptic compounds with more selective activity and lower toxicity continues to be an active area of intensive investigation in medicinal chemistry.
During the recent years, there has been intense investigation of different classes of thiadiazole compounds, many of which possess extensive pharmacological activities, namely, antimicrobial activity, anticonvulsant, antifungal antidiabetic, anti-inflammatory, antioxidant, and antituberculosis activities, and so forth.
The resistance towards available drugs is rapidly becoming a major worldwide problem.
The need to design new compounds to deal with this resistance has become one of the most important areas of research today.
Thiadiazole is a versatile moiety that exhibits a wide variety of biological activities.
Thiadiazole moiety acts as “hydrogen binding domain” and “two-electron donor system.” It also acts as a constrained pharmacophore.
On the basis of the reported literature, we study here thiadiazole compounds and their synthetic methods chemistry and anticonvulsant activity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sharma, Bhawna& Verma, Amita& Prajapati, Sunil& Sharma, Upendra Kumar. 2013. Synthetic Methods, Chemistry, and the Anticonvulsant Activity of Thiadiazoles. International Journal of Medicinal Chemistry،Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-464783
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sharma, Bhawna…[et al.]. Synthetic Methods, Chemistry, and the Anticonvulsant Activity of Thiadiazoles. International Journal of Medicinal Chemistry No. 2013 (2013), pp.1-16.
https://search.emarefa.net/detail/BIM-464783
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sharma, Bhawna& Verma, Amita& Prajapati, Sunil& Sharma, Upendra Kumar. Synthetic Methods, Chemistry, and the Anticonvulsant Activity of Thiadiazoles. International Journal of Medicinal Chemistry. 2013. Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-464783
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-464783
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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