Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients : A Four-Arm Randomized Trial on the Effectiveness of Electroacupuncture
المؤلفون المشاركون
Bartsch, H. H.
Lüdtke, Rainer
Jaroslawski, K.
Rostock, Matthias
Schroeder, Sven
Guethlin, C.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-08-28
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Purpose.
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and dose-limiting side effect of cytostatic drugs.
Since there are no proven therapeutic procedures against CIPN, we were interested to define the role of electroacupuncture (EA) from which preliminary data showed promising results.
Methods.
In a randomized trial with a group sequential adaptive design in patients with CIPN, we compared EA (LV3, SP9, GB41, GB34, LI4, LI11, SI3, and HT3; n=14) with hydroelectric baths (HB, n=14), vitamin B1/B6 capsules (300/300 mg daily; VitB, n=15), and placebo capsules (n=17).
The statistical power in this trial was primarily calculated for proving EA only, so results of HB and VitB are pilot data.
Results.
CIPN complaints improved by 0.8±1.2 (EA), 1.7±1.7 (HB), 1.6±2.0 (VitB), and 1.3±1.3 points (placebo) on a 10-point numeric rating scale without significant difference between treatment groups or placebo.
In addition no significant differences in sensory nerve conduction studies or quality of life (EORTC QLQ-C30) were found.
Conclusions.
The used EA concept, HB, and VitB were not superior to placebo.
Since, contrary to our results, studies with different acupuncture concepts showed a positive effect on CIPN, the effect of acupuncture on CIPN remains unclear.
Further randomized, placebo controlled studies seem necessary.
This trial is registered with DRKS00004448.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rostock, Matthias& Jaroslawski, K.& Guethlin, C.& Lüdtke, Rainer& Schroeder, Sven& Bartsch, H. H.. 2013. Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients : A Four-Arm Randomized Trial on the Effectiveness of Electroacupuncture. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-464856
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rostock, Matthias…[et al.]. Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients : A Four-Arm Randomized Trial on the Effectiveness of Electroacupuncture. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-464856
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rostock, Matthias& Jaroslawski, K.& Guethlin, C.& Lüdtke, Rainer& Schroeder, Sven& Bartsch, H. H.. Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients : A Four-Arm Randomized Trial on the Effectiveness of Electroacupuncture. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-464856
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-464856
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر