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An Increased Ratio of Glycated Albumin to HbA1c Is Associated with the Degree of Liver Fibrosis in Hepatitis B Virus-Positive Patients
المؤلفون المشاركون
Iijima, Hiroko
Sakai, Yoshiyuki
Yoh, Kazunori
Iwata, Kazunari
Nishiguchi, Shuhei
Takashima, Tomoyuki
Hashimoto, Kenji
Aoki, Tomoko
Enomoto, Hirayuki
Ishii, Akio
Iwata, Yoshinori
Saito, Masaki
Yuri, Yukihisa
Tanaka, Hironori
Nakamura, Hideji
Aizawa, Nobuhiro
Imanishi, Hiroyasu
Ikeda, Naoto
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-17
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
In hepatitis B virus- (HBV-) positive patients, the relationship between the metabolic variables and histological degree of liver fibrosis has been poorly investigated.
Methods.
A total of 176 HBV-positive patients were assessed in whom the ratios of glycated albumin-to-glycated hemoglobin (GA/HbA1c) were calculated in order to investigate the relationship with the degree of liver fibrosis.
Results.
The GA/HbA1c ratio increased in association with the severity of fibrosis (METAVIR scores: F0-1: 2.61 ± 0.24, F2: 2.65 ± 0.24, F3: 2.74 ± 0.38, and F4: 2.91 ± 0.63).
The GA/HbA1c ratios were inversely correlated with four variables of liver function: the prothrombin time (PT) percentage (P<0.0001), platelet count (P<0.0001), albumin value (P<0.0001), and cholinesterase value (P<0.0001).
The GA/HbA1c ratio was positively correlated with two well-known markers of liver fibrosis, FIB-4 (P<0.0001) and the AST-to-platelet ratio index (APRI) (P<0.0001).
Furthermore, the GA/HbA1c showed better correlations with two variables of liver function (PT percentage and cholinesterase value) than did FIB-4 and with all four variables than did the APRI.
Conclusion.
The GA/HbA1c ratio is associated with the degree of liver fibrosis in HBV-positive patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Enomoto, Hirayuki& Aizawa, Nobuhiro& Nakamura, Hideji& Sakai, Yoshiyuki& Iwata, Yoshinori& Tanaka, Hironori…[et al.]. 2014. An Increased Ratio of Glycated Albumin to HbA1c Is Associated with the Degree of Liver Fibrosis in Hepatitis B Virus-Positive Patients. Gastroenterology Research and Practice،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-465019
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Enomoto, Hirayuki…[et al.]. An Increased Ratio of Glycated Albumin to HbA1c Is Associated with the Degree of Liver Fibrosis in Hepatitis B Virus-Positive Patients. Gastroenterology Research and Practice No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-465019
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Enomoto, Hirayuki& Aizawa, Nobuhiro& Nakamura, Hideji& Sakai, Yoshiyuki& Iwata, Yoshinori& Tanaka, Hironori…[et al.]. An Increased Ratio of Glycated Albumin to HbA1c Is Associated with the Degree of Liver Fibrosis in Hepatitis B Virus-Positive Patients. Gastroenterology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-465019
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-465019
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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