Image Processing Techniques for Assessing Contractility in Isolated Adult Cardiac Myocytes
المؤلفون المشاركون
Bazan, Carlos
Barba, David Torres
Paolini, Paul
Blomgren, Peter
المصدر
International Journal of Biomedical Imaging
العدد
المجلد 2009، العدد 2009 (31 ديسمبر/كانون الأول 2009)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-02-24
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
We describe a computational framework for the comprehensive assessment of contractile responses of enzymatically dissociated adult cardiac myocytes.
The proposed methodology comprises the following stages: digital video recording of the contracting cell, edge preserving total variation-based image smoothing, segmentation of the smoothed images, contour extraction from the segmented images, shape representation by Fourier descriptors, and contractility assessment.
The different stages are variants of mathematically sound and computationally robust algorithms very well established in the image processing community.
The physiologic application of the methodology is evaluated by assessing overall contraction in enzymatically dissociated adult rat cardiocytes.
Our results demonstrate the effectiveness of the proposed approach in characterizing the true, two-dimensional, “shortening” in the contraction process of adult cardiocytes.
We compare the performance of the proposed method to that of a popular edge detection system in the literature.
The proposed method not only provides a more comprehensive assessment of the myocyte contraction process but also can potentially eliminate historical concerns and sources of errors caused by myocyte rotation or translation during contraction.
Furthermore, the versatility of the image processing techniques makes the method suitable for determining myocyte shortening in cells that usually bend or move during contraction.
The proposed method can be utilized to evaluate changes in contractile behavior resulting from drug intervention, disease modeling, transgeneity, or other common applications to mammalian cardiocytes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bazan, Carlos& Barba, David Torres& Blomgren, Peter& Paolini, Paul. 2010. Image Processing Techniques for Assessing Contractility in Isolated Adult Cardiac Myocytes. International Journal of Biomedical Imaging،Vol. 2009, no. 2009, pp.1-11.
https://search.emarefa.net/detail/BIM-465186
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bazan, Carlos…[et al.]. Image Processing Techniques for Assessing Contractility in Isolated Adult Cardiac Myocytes. International Journal of Biomedical Imaging No. 2009 (2009), pp.1-11.
https://search.emarefa.net/detail/BIM-465186
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bazan, Carlos& Barba, David Torres& Blomgren, Peter& Paolini, Paul. Image Processing Techniques for Assessing Contractility in Isolated Adult Cardiac Myocytes. International Journal of Biomedical Imaging. 2010. Vol. 2009, no. 2009, pp.1-11.
https://search.emarefa.net/detail/BIM-465186
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-465186
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر