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Reversible Audiometric Threshold Changes in Children with Uncomplicated Malaria
المؤلفون المشاركون
Kurtzhals, Jorgen A. L.
Goka, Bamenla Q.
Badoe, Ebenezer
Kitcher, Emmanuel
Rodrigues, Onike P.
Adjei, George O.
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-03-07
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Plasmodium falciparum malaria, as well as certain antimalarial drugs, is associated with hearing impairment in adults.
There is little information, however, on the extent, if any, of this effect in children, and the evidence linking artemisinin combination therapies (ACTs) with hearing is inconclusive.
Methods.
Audiometry was conducted in children with uncomplicated malaria treated with artesunate-amodiaquine (n=37), artemether-lumefantrine (n=35), or amodiaquine (n=8) in Accra, Ghana.
Audiometry was repeated 3, 7, and 28 days later and after 9 months.
Audiometric thresholds were compared with those of a control group of children (n=57) from the same area.
Findings.
During the acute stage, hearing threshold levels of treated children were significantly elevated compared with controls (P<0.001).
The threshold elevations persisted up to 28 days, but no differences in hearing thresholds were evident between treated children and controls after 9 months.
The hearing thresholds of children treated with the two ACT regimens were comparable but lower than those of amodiaquine-treated children during acute illness.
Interpretation.
Malaria is the likely cause of the elevated hearing threshold levels during the acute illness, a finding that has implications for learning and development in areas of intense transmission, as well as for evaluating potential ototoxicity of new antimalarial drugs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Adjei, George O.& Goka, Bamenla Q.& Kitcher, Emmanuel& Rodrigues, Onike P.& Badoe, Ebenezer& Kurtzhals, Jorgen A. L.. 2013. Reversible Audiometric Threshold Changes in Children with Uncomplicated Malaria. Journal of Tropical Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-465813
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Adjei, George O.…[et al.]. Reversible Audiometric Threshold Changes in Children with Uncomplicated Malaria. Journal of Tropical Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-465813
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Adjei, George O.& Goka, Bamenla Q.& Kitcher, Emmanuel& Rodrigues, Onike P.& Badoe, Ebenezer& Kurtzhals, Jorgen A. L.. Reversible Audiometric Threshold Changes in Children with Uncomplicated Malaria. Journal of Tropical Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-465813
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-465813
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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