Sperm Proteomics : Road to Male Fertility and Contraception
المؤلفون المشاركون
Kwon, Woo-Sung
Pang, Myung-Geol
Lee, June-Sub
Rahman, Md. Saidur
المصدر
International Journal of Endocrinology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-01
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Spermatozoa are highly specialized cells that can be easily obtained and purified.
Mature spermatozoa are transcriptionally and translationally inactive and incapable of protein synthesis.
In addition, spermatozoa contain relatively higher amounts of membrane proteins compared to other cells; therefore, they are very suitable for proteomic studies.
Recently, the application of proteomic approaches such as the two-dimensional polyacrylamide gel electrophoresis, mass spectrometry, and differential in-gel electrophoresis has identified several sperm-specific proteins.
These findings have provided a further understanding of protein functions involved in different sperm processes as well as of the differentiation of normal state from an abnormal one.
In addition, studies on the sperm proteome have demonstrated the importance of spermatozoal posttranslational modifications and their ability to induce physiological changes responsible for fertilization.
Large-scale proteomic studies to identify hundreds to thousands of sperm proteins will ultimately result in the development of novel biomarkers that may help to detect fertility, the state of complete contraception, and beyond.
Eventually, these protein biomarkers will allow for a better diagnosis of sperm dysfunctions and aid in drug development.
This paper reviews the recent scientific publications available from the PubMed database to address sperm proteomics and its potential application to characterize male fertility and contraception.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rahman, Md. Saidur& Lee, June-Sub& Kwon, Woo-Sung& Pang, Myung-Geol. 2013. Sperm Proteomics : Road to Male Fertility and Contraception. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-465852
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rahman, Md. Saidur…[et al.]. Sperm Proteomics : Road to Male Fertility and Contraception. International Journal of Endocrinology No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-465852
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rahman, Md. Saidur& Lee, June-Sub& Kwon, Woo-Sung& Pang, Myung-Geol. Sperm Proteomics : Road to Male Fertility and Contraception. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-465852
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-465852
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر