Established Principles and Emerging Concepts on the Interplay between Mitochondrial Physiology and S-(De)nitrosylation : Implications in Cancer and Neurodegeneration
المؤلفون المشاركون
Filomeni, Giuseppe
Di Giacomo, Giuseppina
Rizza, Salvatore
Montagna, Costanza
المصدر
International Journal of Cell Biology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-20، 20ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-13
دولة النشر
مصر
عدد الصفحات
20
التخصصات الرئيسية
الملخص EN
S-nitrosylation is a posttranslational modification of cysteine residues that has been frequently indicated as potential molecular mechanism governing cell response upon redox unbalance downstream of nitric oxide (over)production.
In the last years, increased levels of S-nitrosothiols (SNOs) have been tightly associated with the onset of nitroxidative stress-based pathologies (e.g., cancer and neurodegeneration), conditions in which alterations of mitochondrial homeostasis and activation of cellular processes dependent on it have been reported as well.
In this paper we aim at summarizing the current knowledge of mitochondria-related proteins undergoing S-nitrosylation and how this redox modification might impact on mitochondrial functions, whose impairment has been correlated to tumorigenesis and neuronal cell death.
In particular, emphasis will be given to the possible, but still neglected implication of denitrosylation reactions in the modulation of mitochondrial SNOs and how they can affect mitochondrion-related cellular process, such as oxidative phosphorylation, mitochondrial dynamics, and mitophagy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Di Giacomo, Giuseppina& Rizza, Salvatore& Montagna, Costanza& Filomeni, Giuseppe. 2012. Established Principles and Emerging Concepts on the Interplay between Mitochondrial Physiology and S-(De)nitrosylation : Implications in Cancer and Neurodegeneration. International Journal of Cell Biology،Vol. 2012, no. 2012, pp.1-20.
https://search.emarefa.net/detail/BIM-465944
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Di Giacomo, Giuseppina…[et al.]. Established Principles and Emerging Concepts on the Interplay between Mitochondrial Physiology and S-(De)nitrosylation : Implications in Cancer and Neurodegeneration. International Journal of Cell Biology No. 2012 (2012), pp.1-20.
https://search.emarefa.net/detail/BIM-465944
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Di Giacomo, Giuseppina& Rizza, Salvatore& Montagna, Costanza& Filomeni, Giuseppe. Established Principles and Emerging Concepts on the Interplay between Mitochondrial Physiology and S-(De)nitrosylation : Implications in Cancer and Neurodegeneration. International Journal of Cell Biology. 2012. Vol. 2012, no. 2012, pp.1-20.
https://search.emarefa.net/detail/BIM-465944
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-465944
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر