Helminth Infection Increases the Probability of Indeterminate QuantiFERON Gold in Tube Results in Pregnant Women
المؤلفون المشاركون
Desta, Kassu
Howe, Rawleigh
Gebreegziabiher, Dawit
Abebe, Markos
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-19
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
Approximately one-third of the world population is infected with M.
tuberculosis and helminths (Kariminia et al.
(2009), Walson et al.
(2010)).
Pregnancy and Helminth infection are known to suppress the TH1 response (Kariminia et al.
(2009), Elias et al.
(2006)) on which the QuantiFERON Gold in Tube (QFT-GIT) assay, that measures the released IFN-γ upon in vitro stimulation with mycobacterial antigens, relies on (Thomas et al.
(2010)).
Objective.
To determine whether QFT-GIT indeterminate result is significantly associated with helminth infection or not.
Methods.
In this cross-sectional study, eighty-five pregnant mothers were screened for parasitic and LTBI using Kato-Katz and QFT-GIT test-respectively, Result.
The prevalence of helminth infection in pregnant mothers was 23 (27%) of this 17 (20%) was due to Schistosoma mansoni.
Among the total of 85 study participants 26.8% were QFT-GIT positive and 14 (17%) had indeterminate results.
Three samples (21.4%) were randomly selected from the indeterminate QFT-GIT results and retested to check the reproducibility of the assay and remained indeterminate.
QFT-GIT indeterminate result showed significant association with helminth infection.
Conclusion.
Helminth infections were significantly associated with indeterminate QFT-GIT results in pregnant mothers.
Therefore further study is important to evaluate the possible effect of helminth infection by excluding the effect of pregnancy, as pregnancy also downregulates cellular immunity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gebreegziabiher, Dawit& Desta, Kassu& Howe, Rawleigh& Abebe, Markos. 2014. Helminth Infection Increases the Probability of Indeterminate QuantiFERON Gold in Tube Results in Pregnant Women. BioMed Research International،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-466120
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gebreegziabiher, Dawit…[et al.]. Helminth Infection Increases the Probability of Indeterminate QuantiFERON Gold in Tube Results in Pregnant Women. BioMed Research International No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-466120
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gebreegziabiher, Dawit& Desta, Kassu& Howe, Rawleigh& Abebe, Markos. Helminth Infection Increases the Probability of Indeterminate QuantiFERON Gold in Tube Results in Pregnant Women. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-466120
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-466120
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر