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Pediatric Renal Transplantation in a Highly Sensitised Child—8 Years On
المؤلفون المشاركون
Awan, Atif
Keogan, Mary
Little, Dilly
Gill, Denis
Hickey, David
Conlon, Peter J.
Quinlan, Catherine
Waldron, Mary
المصدر
Case Reports in Transplantation
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-01-26
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Highly sensitised children have markedly reduced chances of receiving a successful deceased donor renal transplant, increased risk of rejection, and decreased graft survival.
There is limited experience with the long-term followup of children who have undergone desensitization.
Following 2 failed transplants, our patient was highly sensitised.
She had some immunological response to intravenous immunoglobulin (IVIg) but this was not sustained.
We developed a protocol involving sequential therapies with rituximab, IVIg, and plasma exchange.
Immunosuppressant therapy at transplantation consisted of basiliximab, tacrolimus, mycophenolate mofetil, and steroids.
At the time of transplantation, historical crossmatch was ignored.
Current CDC crossmatch was negative, but T and B cell flow crossmatch was positive, due to donor-specific HLA Class I antibodies.
Further plasma exchange and immunoglobulin therapy were given pre- and postoperatively.
Our patient received a deceased donor-kidney-bearing HLA antigens to which she originally had antibodies, which would have precluded transplant.
The graft kidney continues to function well 8 years posttransplant.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Quinlan, Catherine& Awan, Atif& Gill, Denis& Waldron, Mary& Little, Dilly& Hickey, David…[et al.]. 2012. Pediatric Renal Transplantation in a Highly Sensitised Child—8 Years On. Case Reports in Transplantation،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-466672
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Quinlan, Catherine…[et al.]. Pediatric Renal Transplantation in a Highly Sensitised Child—8 Years On. Case Reports in Transplantation No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-466672
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Quinlan, Catherine& Awan, Atif& Gill, Denis& Waldron, Mary& Little, Dilly& Hickey, David…[et al.]. Pediatric Renal Transplantation in a Highly Sensitised Child—8 Years On. Case Reports in Transplantation. 2012. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-466672
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-466672
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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