Metabolic Effects of Sucralose on Environmental Bacteria

المؤلفون المشاركون

Bowers, Doria
Swenson, Janice
Coughlin, Charles
Omran, Arthur
Ahearn, Gregory

المصدر

Journal of Toxicology

العدد

المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2013-12-03

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

العلوم الطبية والصيدلة والعلوم الصحية
الطب البشري

الملخص EN

Sucralose was developed as a low cost artificial sweetener that is nonmetabolizable in humans.

Sucralose can withstand changes in pH and temperature and is not degraded by the wastewater treatment process.

Since the molecule can withstand heat, acidification, and microbial degradation, it is accumulating in the environment and has been found in wastewater, estuaries, rivers, and the Gulf Stream.

Environmental isolates were cultured in the presence of sucralose looking for potential sucralose metabolism or growth acceleration responses.

Sucralose was found to be nonnutritive and demonstrated bacteriostatic effects on all six isolates.

This growth inhibition was directly proportional to the concentration of sucralose exposure, and the amount of the growth inhibition appeared to be species-specific.

The bacteriostatic effect may be due to a decrease in sucrose uptake by bacteria exposed to sucralose.

We have determined that sucralose inhibits invertase and sucrose permease.

These enzymes cannot catalyze hydrolysis or be effective in transmembrane transport of the sugar substitute.

Current environmental concentrations should not have much of an effect on environmental bacteria since the bacteriostatic effect seems to be consecration based; however, as sucralose accumulates in the environment, we must consider it a contaminant, especially for microenvironments.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Omran, Arthur& Ahearn, Gregory& Bowers, Doria& Swenson, Janice& Coughlin, Charles. 2013. Metabolic Effects of Sucralose on Environmental Bacteria. Journal of Toxicology،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-466898

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Omran, Arthur…[et al.]. Metabolic Effects of Sucralose on Environmental Bacteria. Journal of Toxicology No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-466898

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Omran, Arthur& Ahearn, Gregory& Bowers, Doria& Swenson, Janice& Coughlin, Charles. Metabolic Effects of Sucralose on Environmental Bacteria. Journal of Toxicology. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-466898

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-466898