Metabolic Effects of Sucralose on Environmental Bacteria
Joint Authors
Bowers, Doria
Swenson, Janice
Coughlin, Charles
Omran, Arthur
Ahearn, Gregory
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Pharmacy, Health & Medical Sciences
Medicine
Abstract EN
Sucralose was developed as a low cost artificial sweetener that is nonmetabolizable in humans.
Sucralose can withstand changes in pH and temperature and is not degraded by the wastewater treatment process.
Since the molecule can withstand heat, acidification, and microbial degradation, it is accumulating in the environment and has been found in wastewater, estuaries, rivers, and the Gulf Stream.
Environmental isolates were cultured in the presence of sucralose looking for potential sucralose metabolism or growth acceleration responses.
Sucralose was found to be nonnutritive and demonstrated bacteriostatic effects on all six isolates.
This growth inhibition was directly proportional to the concentration of sucralose exposure, and the amount of the growth inhibition appeared to be species-specific.
The bacteriostatic effect may be due to a decrease in sucrose uptake by bacteria exposed to sucralose.
We have determined that sucralose inhibits invertase and sucrose permease.
These enzymes cannot catalyze hydrolysis or be effective in transmembrane transport of the sugar substitute.
Current environmental concentrations should not have much of an effect on environmental bacteria since the bacteriostatic effect seems to be consecration based; however, as sucralose accumulates in the environment, we must consider it a contaminant, especially for microenvironments.
American Psychological Association (APA)
Omran, Arthur& Ahearn, Gregory& Bowers, Doria& Swenson, Janice& Coughlin, Charles. 2013. Metabolic Effects of Sucralose on Environmental Bacteria. Journal of Toxicology،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-466898
Modern Language Association (MLA)
Omran, Arthur…[et al.]. Metabolic Effects of Sucralose on Environmental Bacteria. Journal of Toxicology No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-466898
American Medical Association (AMA)
Omran, Arthur& Ahearn, Gregory& Bowers, Doria& Swenson, Janice& Coughlin, Charles. Metabolic Effects of Sucralose on Environmental Bacteria. Journal of Toxicology. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-466898
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466898