Calcific Uremic Arteriolopathy on Multimodal Combination Therapy : Still Unmet Goal

المؤلفون المشاركون

Manickam, Valli
Doherty, Susan Lynette
Malabu, Usman Hammawa
Sangla, Kunwarjit Singh
Kan, George

المصدر

International Journal of Nephrology

العدد

المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2012-02-20

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

الأمراض
الطب البشري

الملخص EN

Background.

Calcific uremic arteriolopathy (CUA) or calciphylaxis though generally noted for its high mortality, recent case reports have shown promising results using single agent therapies.

However, it is not clear whether combination therapeutic agents will improve course of the disease.

Objective.

To determine clinical outcome in subjects with CUA on multimodal treatment.

Methods.

All patients with end-stage renal failure (ESRF) at The Townsville Hospital, Australia, from April 1, 2006, to March 31, 2011, with diagnosis of CUA were retrospectively studied.

Results.

Six subjects with CUA (4 females and 2 males) were on various combination therapeutic agents comprising sodium thiosulphate, hyperbaric oxygen, prednisolone, cinacalcet, and parathyroidectomy in addition to intensified haemodialysis, specialist local wound care, and antibiotics.

The wounds failed to heal in 3 patients while 5 of the 6 subjects died; cause of death being sepsis in 3 and myocardial infarction in 2.

Conclusion.

Prognosis of CUA remains poor in spite of multimodal combination therapy.

Further prospective studies on a larger population are needed to verify our findings.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Malabu, Usman Hammawa& Manickam, Valli& Kan, George& Doherty, Susan Lynette& Sangla, Kunwarjit Singh. 2012. Calcific Uremic Arteriolopathy on Multimodal Combination Therapy : Still Unmet Goal. International Journal of Nephrology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-468355

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Malabu, Usman Hammawa…[et al.]. Calcific Uremic Arteriolopathy on Multimodal Combination Therapy : Still Unmet Goal. International Journal of Nephrology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-468355

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Malabu, Usman Hammawa& Manickam, Valli& Kan, George& Doherty, Susan Lynette& Sangla, Kunwarjit Singh. Calcific Uremic Arteriolopathy on Multimodal Combination Therapy : Still Unmet Goal. International Journal of Nephrology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-468355

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-468355