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The Role of Large-Format Histopathology in Assessing Subgross Morphological Prognostic Parameters : A Single Institution Report of 1000 Consecutive Breast Cancer Cases
المؤلف
المصدر
International Journal of Breast Cancer
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-10-21
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Breast cancer subgross morphological parameters (disease extent, lesion distribution, and tumor size) provide significant prognostic information and guide therapeutic decisions.
Modern multimodality radiological imaging can determine these parameters with increasing accuracy in most patients.
Large-format histopathology preserves the spatial relationship of the tumor components and their relationship to the resection margins and has clear advantages over traditional routine pathology techniques.
We report a series of 1000 consecutive breast cancer cases worked up with large-format histology with detailed radiological-pathological correlation.
We confirmed that breast carcinomas often exhibit complex subgross morphology in both early and advanced stages.
Half of the cases were extensive tumors and occupied a tissue space ≥40 mm in its largest dimension.
Because both in situ and invasive tumor components may exhibit unifocal, multifocal, and diffuse lesion distribution, 17 different breast cancer growth patterns can be observed.
Combining in situ and invasive tumor components, most cases fall into three aggregate growth patterns: unifocal (36%), multifocal (35%), and diffuse (28%).
Large-format histology categories of tumor size and disease extent were concordant with radiological measurements in approximately 80% of the cases.
Noncalcified, low-grade in situ foci, and invasive tumor foci <5 mm were the most frequent causes of discrepant findings.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tot, Tibor. 2012. The Role of Large-Format Histopathology in Assessing Subgross Morphological Prognostic Parameters : A Single Institution Report of 1000 Consecutive Breast Cancer Cases. International Journal of Breast Cancer،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-468757
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tot, Tibor. The Role of Large-Format Histopathology in Assessing Subgross Morphological Prognostic Parameters : A Single Institution Report of 1000 Consecutive Breast Cancer Cases. International Journal of Breast Cancer No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-468757
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tot, Tibor. The Role of Large-Format Histopathology in Assessing Subgross Morphological Prognostic Parameters : A Single Institution Report of 1000 Consecutive Breast Cancer Cases. International Journal of Breast Cancer. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-468757
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-468757
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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